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Collaborations and top research areas from the last five years
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Mechanism and inhibition of organic and enzymatic isomerizations
Murkin, A. (PI), Hirschi, J. (CoI), Hirschi, J. (CoI), Hirschi, J. (CoI) & Murkin, A. (PI)
10/1/23 → 09/30/26
University at Buffalo, Binghamton University
Project: Research
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Covalent and Transition State Inhibitor Design
Murkin, A. (PI) & Hirschi, J. (CoI)
08/1/18 → 07/31/22
Project: Research
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CAREER: Determination of Enzyme Mechanisms Using New Kinetic Isotope Effect Approaches
Murkin, A. (PI)
05/1/13 → 05/31/19
Project: Research
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Methionine Salvage Enzyme Uses a Unique Mechanism to Overcome a Challenging Aldose–Ketose Isomerization
Ubayawardhana, S. T., Das, T., Corio, S. A., Hirschi, J. S. & Murkin, A. S., Dec 3 2025, In: Journal of the American Chemical Society. 147, 48, p. 44236-44247 12 p.Binghamton University, University at Buffalo
Research output: Contribution to journal › Article › peer-review
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Mycobacterium tuberculosis D-alanine:D-alanine ligase as a case study in the measurement of competitive kinetic isotope effects for dimerization reactions
Fernandez, P. L. & Murkin, A. S., May 2025, In: Bioorganic Chemistry. 158, 108332.Research output: Contribution to journal › Article › peer-review
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Demystifying Functional Parameters for Irreversible Enzyme Inhibitors
Heppner, D. E., Ogboo, B. C., Urul, D. A., May, E. W., Schaefer, E. M., Murkin, A. S. & Gehringer, M., Sep 12 2024, In: Journal of Medicinal Chemistry. 67, 17, p. 14693-14696 4 p.Research output: Contribution to journal › Editorial
Open Access25 Scopus citations -
Kinetic characterization of methylthio-D-ribose-1-phosphate isomerase
Veeramachineni, V. M., Ubayawardhana, S. T. & Murkin, A. S., Jan 2023, New Experimental Probes for Enzyme Specificity and Mechanism. Richard, J. P. & Moran, G. R. (eds.). Academic Press Inc., p. 279-318 40 p. (Methods in Enzymology; vol. 685).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Scopus citations -
Covalent Adduct Formation in Methylthio- d -ribose-1-phosphate Isomerase: Reaction Intermediate or Artifact?
Veeramachineni, V. M., Ubayawardhana, S. T. & Murkin, A. S., Jun 7 2022, In: Biochemistry. 61, 11, p. 1124-1135 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations