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Collaborations and top research areas from the last five years
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Sphingolipids in Cancer Biology and Therapy
Hannun, Y. (PI), Airola, M. (CoPI), Canals, D. (CoPI), Clarke, C. (CoPI), Haley, J. (CoPI), Luberto, C. (CoPI), Mao, C. (CoPI), Velazquez, F. N. (CoPI) & Yang, J. (CoPI)
09/1/25 → 08/31/26
Project: Research
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Role of ACER2 in cancer chemoresistance and metastasis
Mao, C. (PI), Haley, J. (CoPI) & Yang, J. (CoPI)
07/1/22 → 06/30/26
Project: Research
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Sphingoloids in Cancer Biology and Therapy
Hannun, Y. (PI), Frohman, M. (CoPI), Haley, J. (CoPI), Luberto, C. (CoPI), Mao, C. (CoPI) & Yang, J. (CoI)
09/1/23 → 08/31/25
Project: Research
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Sphingoloids in Cancer Biology and Therapy
Hannun, Y. (PI), Frohman, M. (CoPI), Haley, J. (CoPI), Luberto, C. (CoPI), Mao, C. (CoPI) & Yang, J. (CoI)
09/1/22 → 08/31/23
Project: Research
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Sphingoloids in Cancer Biology and Therapy
Hannun, Y. (PI), Frohman, M. (CoPI), Haley, J. (CoPI), Luberto, C. (CoPI), Mao, C. (CoPI) & Yang, J. (CoI)
09/1/21 → 08/31/22
Project: Research
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Ceramide(d18:1/18:1)-NDUFA6 interaction inactivates respiratory complex I to attenuate oxidative-stress-driven pathogenesis in liver ischemia/ reperfusion injury
Wang, K., Liao, L., Liang, H., Huang, P., Li, Q., Zhuang, B., Xie, C., Mo, X., Deng, X., Li, J., Lei, Y., Zeng, M., Mao, C., Xu, R., Liu, C., Wu, X., Zhou, J., Wang, B., Li, Y. & Li, C., May 2025, In: JCI Insight. 10, 10, e187083.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sphingolipid metabolism dysregulation: A cause for lung cancer development, progression, and resistance to therapies
Mao, C., Jun 2025, In: Chinese Medical Journal Pulmonary and Critical Care Medicine. 3, 2, p. 88-96 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Sphingosine simultaneously inhibits nuclear import and activates PP2A by binding importins and PPP2R1A
Jayashankar, V., Kubiniok, P., McCracken, A. N., Gentry, R. G., Eckenstein, K. H., Sernissi, L., Vece, V., Garsi, J. B., Valles, S. Y., Jung, S., Hoffman, N. C., Perrochon, A. S., Selwan, E. M., Finicle, B. T., Pitman, M., Lin, D. W., Bonneil, É., Xu, R., Mao, C. & Kaiser, P. & 6 others, , Aug 18 2025, In: EMBO Journal. 44, 16, p. 4473-4498 26 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction
Liao, L., Liu, Z., Liu, L., Huang, C., Li, Y., Mao, C., Xu, R., Liu, H., Liu, C., Peng, Y., Lei, T., Liang, H., Yu, S., Qian, J., Wu, X., Wang, B., Lin, Y., Zhou, J., Li, Q. & Li, C. & 1 others, , Dec 2025, In: Nature Communications. 16, 1, 2112.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Inhibitory effect of Porphyromonas gingivalis-derived phosphoethanolamine dihydroceramide on acid ceramidase expression in oral squamous cells
Yamada, C., Ho, A., Nusbaum, A., Xu, R., Davey, M. E., Nichols, F., Mao, C. & Movila, A., May 2023, In: Journal of Cellular and Molecular Medicine. 27, 9, p. 1290-1295 6 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations