Grants & Projects per year
Personal profile
Research interests
Dr. Montrose's lab is focused on understanding and modulating host intrinsic and extrinsic factors in the GI tract to prevent and treat colorectal cancer (CRC) and inflammatory bowel disease (IBD). Projects include: 1) Disrupting tumor cell metabolism through targeting synthesis and exogenous availability of nutrients for CRC prevention and treatment; 2) Dietary and pharmacological approaches to alter the influence of gut luminal factors on intestinal tumor development; 3) Modulating immune cell metabolism to ameliorate IBD; 4) Understanding the pathogenesis of the gut injury response to enhance wound healing.
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Grants & Projects
- 10 Finished
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Defining the Role of Pea-derived Protein in Inflammatory Bowel Diseases
Montrose, D. (PI)
07/1/23 → 09/30/24
Project: Research
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Inhibiting Serine as a Novel Treatment for Intestinal Fibrosis
Montrose, D. (PI)
06/1/23 → 05/31/24
Project: Research
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PCHI - Pea Protein Consumption to Promote Gut Health in Humans
Montrose, D. (PI), Aroniadis, O. C. (CoPI) & Connolly-Schoonen, J. (CoPI)
USDA Agricultural Research Service
09/1/22 → 12/31/25
Project: Research
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Inhibiting Serine Synthesis as a Novel Treatment for Intestinal Fibrosis
Montrose, D. (PI)
06/1/22 → 05/31/23
Project: Research
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Demonstrating the Benefits of Pea-derived Protein Consumption in Colon Cancer
Montrose, D. (PI)
01/1/21 → 12/31/22
Project: Research
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Dietary protein as a regulator of colitis and colorectal cancer
Thaker, S. D., Gogokhia, L. & Montrose, D. C., Jul 2026, In: Current Opinion in Gastroenterology. 42, 4, p. 239-246 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Dietary Protein Source Mediates Colitis Pathogenesis Through Bacterial Modulation of Bile Acids
Gray, S. M., Wood, M. C., Mulkeen, S. C., Ahmed, S., Thaker, S. D., Chen, B., Sander, W. R., Bibeva, V., Zhang, X., Yang, J., Herzog, J. W., Moss, A. D., Zhang, S., Dogan, B., Simpson, K. W., Sartor, R. B. & Montrose, D. C., 2026, In: CMGH. 20, 10, 101825.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms
Mulkeen, S. C., Saha, S., Ferrara, C. R., Bibeva, V., Wood, M. C., Bai, J. D. K., Peres, T. V., Martinez-Martinez, D., Montoya, A., Shliaha, P., Cabreiro, F. & Montrose, D. C., Jul 1 2025, In: Molecular Cancer Therapeutics. 24, 7, p. 1099-1110 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A Comprehensive Metabolomic and Microbial Analysis Following Dietary Amino Acid Reduction in Mice
Al-Ishaq, R. K., Ferrara, C. R., Stephan, N., Krumsiek, J., Suhre, K. & Montrose, D. C., Dec 2024, In: Metabolites. 14, 12, 706.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Metabolic regulation of the mitochondrial immune checkpoint
Montrose, D. C., Saha, S. & Galluzzi, L., 2024, In: OncoImmunology. 13, 1, 2394247.Research output: Contribution to journal › Editorial
Open Access