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Dive into the research topics where James O'Donnell is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Initiative for Maximizing Student Development at University at Buffalo
Dubocovich, M. (PI), Liu, X. (CoI), O'Donnell, J. (CoI), Reynolds, J. (CoI), Wichlacz, S. (CoI), Sodano, S. (CoI) & Sprowl, J. (CoI)
National Institute of General Medical Sciences
02/1/22 → 01/31/27
Project: Research
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Role of PDE2A in mitochondrial dysfunction in Alzheimer's disease
O'Donnell, J. (CoI) & Xu, Y. (PI)
08/15/21 → 01/31/22
Project: Research
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SBIR: PDE4B Inhibitors for Treating Major Depression
O'Donnell, J. (CoPI) & Xu, Y. (PI)
National Institute of Mental Health
11/25/13 → 07/31/16
Project: Research
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Protective effects of phosphodiesterase 2 inhibitor against Aβ1-42 induced neuronal toxicity
Yan, Y., Gao, S., Avasthi, S., Zhao, Y., Ye, J., Tao, Y., Wang, W., Zhu, X., Du, F., O'Donnell, J. M. & Xu, Y., Aug 1 2022, In: Neuropharmacology. 213, 109128.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events
Zhao, F., Xu, Y., Gao, S., Qin, L., Austria, Q., Siedlak, S. L., Pajdzik, K., Dai, Q., He, C., Wang, W., O’Donnell, J. M., Tang, B. & Zhu, X., Dec 2021, In: Molecular Neurodegeneration. 16, 1, 70.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations -
A Novel PDE4D Inhibitor BPN14770 Reverses Scopolamine-Induced Cognitive Deficits via cAMP/SIRT1/Akt/Bcl-2 Pathway
Wang, Y., Gao, S., Zheng, V., Chen, L., Ma, M., Shen, S., Qu, J., Zhang, H., Gurney, M. E., O’Donnell, J. M. & Xu, Y., Dec 10 2020, In: Frontiers in Cell and Developmental Biology. 8, 599389.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior
Zhu, M. J., Shi, J., Chen, Y., Huang, G., Zhu, X. W., Zhang, S., Huang, X. F., Song, G. Q., Zhang, H. T., Ke, H. M., O’Donnell, J. M., Wang, L. Q. & Xu, Y., Nov 1 2020, In: Psychopharmacology. 237, 11, p. 3215-3224 10 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Single housing-induced effects on cognitive impairment and depression-like behavior in male and female mice involve neuroplasticity-related signaling
Liu, N., Wang, Y., An, A. Y., Banker, C., Qian, Y. H. & O'Donnell, J. M., Jul 1 2020, In: European Journal of Neuroscience. 52, 1, p. 2694-2704 11 p.Research output: Contribution to journal › Article › peer-review
73 Scopus citations