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Collaborations and top research areas from the last five years
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Pharmacokinetic / Pharmacodynamic Optimization of ADC Therapy for Acute Myeloid Leukemia
Balthasar, J. (PI) & Shah, D. (CoI)
01/1/23 → 01/31/28
Project: Research
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SBIR A1: Lead Optimization and Evaluation of Anti-SN38 Payload Binding Selectivity Enhancers
Balthasar, J. (PI)
09/15/21 → 08/31/23
Project: Research
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The role of oral spirochete virulence factors in the impairment of neutrophil response
Kay, M. (PI), Balthasar, J. (CoI), Qu, J. (CoI), Sharma, A. (CoI) & Wilding, G. (CoI)
National Institute of Dental & Craniofacial Res
09/1/18 → 08/31/25
Project: Research
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Exploring New Virulence Factors of the Oral Spirochete Treponema denticola
Balthasar, J. (CoI) & Li, C. (PI)
National Institute of Dental & Craniofacial Res
06/1/16 → 10/4/17
Project: Research
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Assessment of the Effects of Single-Domain Anti-Idiotypic Distribution Enhancers on the Disposition of Trastuzumab and on the Efficacy of a PE24-Trastuzumab Immunotoxin
Chen, P., Zhang, Y., Bordeau, B. M. & Balthasar, J. P., May 2025, In: Cancers. 17, 9, 1468.Research output: Contribution to journal › Article › peer-review
Open Access -
Camptothein-Based Anti-Cancer Therapies and Strategies to Improve Their Therapeutic Index
Gong, J., Zhang, W. & Balthasar, J. P., Mar 2025, In: Cancers. 17, 6, 1032.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
Improving the Therapeutic Selectivity of Trastuzumab Deruxtecan Using 8C2 Fab Fragments
Gong, J., Bordeau, B. M. & Balthasar, J. P., Aug 2025, In: AAPS Journal. 27, 4, 106.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Investigations of Influence of Antibody Binding Kinetics on Tumor Distribution and Anti-Tumor Efficacy
Chen, P., Bordeau, B. M., Zhang, W. & Balthasar, J. P., Aug 2025, In: AAPS Journal. 27, 4, 91.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment
Zippelius, A., Tolaney, S. M., Tarantino, P., Balthasar, J. P. & Thurber, G. M., Dec 2025, In: Nature Reviews Cancer. 25, 12, p. 925-944 20 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations