Personal profile
Research interests
- Human organ-on-a-chip and organoid
- BioMEMs and soft robotics
- Microfabrication and biofabrication
- Bio-optics and optofluidics
- Bio-inspired engineering
Biography
Jay Paek is interested in developing microphysiological systems based on organ-on-a-chip and organoid technologies to study disease processes in the human respiratory and vascular systems. Previously, he was a research associate in the Department of Bioengineering at University of Pennsylvania, where he worked on in vitro modeling of human tissues and organs.
Prior to his postdoctoral work, Paek received his PhD in electrical engineering from Iowa State University, with his primary research centered on the design, fabrication and application of bio-inspired elastomeric microsystems. He is currently an assistant professor in the Department of Electrical and Computer Engineering at Binghamton University (State University of New York).
Related documents
Education/Academic qualification
Postdoc training: University of Pennsylvania
PhD, Iowa State University
ASJC Scopus Subject Areas
- General Engineering
- Electrical and Electronic Engineering
- Biotechnology
- Cell Biology
Researcher Selected Keywords
- Human organ-on-a-chip and organoid
- BioMEMs and soft robotics
- Microfabrication and biofabrication
- Bio-optics and optofluidics
- Bio-inspired engineering
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Collaborations and top research areas from the last five years
Grants & Projects
- 1 Active
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Investigating the interplay between polymorphic a-syn fibril conformation and cell-dependent pathology
Paek, J. (PI)
08/1/24 → 07/31/26
Project: Research
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Microengineering of the capillary interface of midbrain dopaminergic neurons to study Parkinson’s disease vascular alterations
Alim, A., Baek, Y., Lee, M. & Paek, J., Dec 2026, In: Communications Engineering. 5, 1, 23.Research output: Contribution to journal › Article › peer-review
Open Access -
A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors
Liu, H., Noguera-Ortega, E., Dong, X., Lee, W. D., Chang, J., Aydin, S. A., Li, Y., Shin, Y., Shi, X., Liousia, M., Martinez, M. C., Brotman, J. J., Kim, S., Chen, Z., Wang, A., Ou, Z., Paek, J., Park, J. Y., Liu, A. & Hu, H. & 12 others, , 2025, (Accepted/In press) In: Nature Biotechnology.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Geometric engineering of organoid culture for enhanced organogenesis in a dish
Park, S. E., Kang, S., Paek, J., Georgescu, A., Chang, J., Yi, A. Y., Wilkins, B. J., Karakasheva, T. A., Hamilton, K. E. & Huh, D. D., Nov 2022, In: Nature Methods. 19, 11, p. 1449-1460 12 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Soft robotic constrictor for in vitro modeling of dynamic tissue compression
Paek, J., Song, J. W., Ban, E., Morimitsu, Y., Osuji, C. O., Shenoy, V. B. & Huh, D. D., Dec 2021, In: Scientific Reports. 11, 1, 16478.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues
Paek, J., Park, S. E., Lu, Q., Park, K. T., Cho, M., Oh, J. M., Kwon, K. W., Yi, Y. S., Song, J. W., Edelstein, H. I., Ishibashi, J., Yang, W., Myerson, J. W., Kiseleva, R. Y., Aprelev, P., Hood, E. D., Stambolian, D., Seale, P., Muzykantov, V. R. & Huh, D., Jul 23 2019, In: ACS Nano. 13, 7, p. 7627-7643 17 p.Research output: Contribution to journal › Article › peer-review
212 Scopus citations