Personal profile
Research interests
- Molecular mechanism of environmental arsenic and chromium-induced toxicology and carcinogenesis
- Interaction of metals with zinc-containing proteins, and zinc supplement as a chemoprevention strategy for reducing arsenic toxicity and carcinogenesis
- Arsenic co-carcinogenesis in enhancing UV-induced DNA damage, inhibition of DNA repair, and formation of mutational signatures assessed by whole genome sequencing
- Molecular mechanism of brain injury and neuroprotection in stroke
In vivo imaging of oxidative stress and tissue oxygenation
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Collaborations and top research areas from the last five years
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Madeira Fellowship: Defining Critical Temporal Windows of Microglial Activity in Stroke Recovery
Nadkarni, N. (PI), Liu, K. J. (CoPI) & Madeira, M. (CoPI)
American Heart Association Incorporated
01/1/26 → 12/31/26
Project: Research
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Endogenous Zinc Protoporphyrin in Intracerebral Hemorrhage
Liu, K. J. (PI), Yang, J. (CoPI) & Pan, R. (CoPI)
National Inst of Neurological Disorders & Stroke
12/1/24 → 11/30/26
Project: Research
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Chromosome Instability Drives Metal-Induced Lung Cancer (Year 2)
Liu, K. J. (PI)
National Inst of Environmental Health Sciences
07/1/23 → 06/30/24
Project: Research
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Developmental Exposures to Arsenic: Pneumonia, Immunity, and Microbiomes (DEAPIM)
Liu, K. J. (PI)
National Inst of Environmental Health Sciences
08/1/22 → 12/31/25
Project: Research
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1,4-Dioxane Induces Epithelial-Mesenchymal Transition and Carcinogenesis in an Nrf2-Dependent Manner
Wang, Z., Thakur, C., Bi, Z., Qiu, Y., Zhang, W., Ji, H., Venkatesan, A. K., Cherukuri, S., Liu, K. J., Haley, J. D., Mao, X., Meliker, J. & Chen, F., May 2025, In: Journal of Extracellular Vesicles. 14, 5, e70072.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Normobaric hyperoxia combined with endovascular treatment for acute ischaemic stroke in China (OPENS-2 trial): a multicentre, randomised, single-blind, sham-controlled trial
Li, W., Lan, J., Wei, M., Liu, L., Hou, C., Qi, Z., Li, C., Jiao, L., Yang, Q., Chen, W., Liu, S., Yue, X., Dong, Q., Yuan, H., Gao, Z., Wu, X., Wen, C., Li, T., Jiang, C. & Li, D. & 10 others, , Feb 8 2025, In: The Lancet. 405, 10477, p. 486-497 12 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Nrf2/cyclooxygenase 2 signaling in Cr(VI)-induced carcinogenesis
Zhao, L., Wang, Y. F., Adamcakova-Dodd, A., Thorne, P. S., Islam, R., Liu, K. J., Chen, F., Luo, J. & Liu, L. Z., Feb 2025, In: Ecotoxicology and Environmental Safety. 291, 117800.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The Association of Serum Biomarkers With Symptomatic Hemorrhagic Transformation in Acute Ischemic Stroke Patients: A Combined Retrospective and Prospective Study
Yuan, S., Gao, D., Shi, W., Zhao, Y., Guo, Z., Chen, X., Li, W., Liu, K. J., Yang, J., Zhang, Y., Ji, X. & Qi, Z., Mar 2025, In: CNS Neuroscience and Therapeutics. 31, 3, e70321.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Trivalent chromium interacts directly with acetylated lysine
Wise, R. M., Jiang, T., Meaza, I., Feng, C., Wise, J. P., Liu, K. J. & Zhou, X., Dec 2025, In: Journal of Trace Elements in Medicine and Biology. 92, 127782.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations