Melanie Comito

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1 Similar Profiles

11 Active
14 Finished

A phase 3 randomized trial of inotuzumab ozomagicin
Comito, M. (PI)
Public Health Institute
12/18/24 → 12/17/26
Upstate Medical University
Project: Research
A phase 3 randomized study of selumetinib versus carboplatin/vincristine in newly diagnosed or previously untreated neurofibromatosis type i associated low grade glioma
Comito, M. (PI) & Monteleone, P. (PI)
Public Health Institute
07/15/22 → 07/14/26
Upstate Medical University
Project: Research
An open label feasibility study to assess the safety and pharmacokinetics of enasidenib in pediaric patients with relapsed/refractory acute myeloid leukemia R/R-AML with an isocitrate ehydrogenzse 2IDH1 mutation
Comito, M. (PI) & Monteleone, P. (PI)
Public Health Institute
07/1/22 → 06/30/26
Upstate Medical University
Project: Research
A5481092: A phase 2 study to evaluate the safety and pharfmacokinetics of palbociclib (IBRANCE) in combination with irinotecan and temozolomide in pediatric patients with recurrent or refractory solid tumors
Comito, M. (PI) & Monteleone, P. (PI)
Public Health Institute
05/19/22 → 05/18/26
Upstate Medical University
Project: Research
ACCL2031-A phase 3 randomized placebo controlled trial evaluationg memantine for neurocognitive protection in children undergoing cranial radiotherapy as part of treatment for primary central nervous system tumorw
Comito, M. (PI) & Monteleone, P. (PI)
Mayo Foundation for Medical Education and Research
05/10/22 → 10/31/26
Upstate Medical University
Project: Research

24 Article
2 Review article
1 Letter

Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study
Ercan, A. B., Aronson, M., Fernandez, N. R., Chang, Y., Levine, A., Liu, Z. A., Negm, L., Edwards, M., Bianchi, V., Stengs, L., Chung, J., Al-Battashi, A., Reschke, A., Lion, A., Ahmad, A., Lassaletta, A., Reddy, A. T., Al-Darraji, A. F., Shah, A. C. & Van Damme, A. & 108 others, Bendel, A., Rashid, A., Margol, A. S., Kelly, B. L., Pencheva, B., Heald, B., Lemieux-Anglin, B., Crooks, B., Koschmann, C., Gilpin, C., Porter, C. C., Gass, D., Samuel, D., Ziegler, D. S., Blumenthal, D. T., Kuo, D. J., Hamideh, D., Basel, D., Khuong-Quang, D. A., Stearns, D., Opocher, E., Carceller, F., Baris Feldman, H., Toledano, H., Winer, I., Scheers, I., Fedorakova, I., Su, J. M., Vengoechea, J., Sterba, J., Knipstein, J., Hansford, J. R., Gonzales-Santos, J. R., Bhatia, K., Bielamowicz, K. J., Minhas, K., Nichols, K. E., Cole, K. A., Penney, L., Hjort, M. A., Sabel, M., Gil-da-Costa, M. J., Murray, M. J., Miller, M., Blundell, M. L., Massimino, M., Al-Hussaini, M., Al-Jadiry, M. F., Comito, M. A., Osborn, M., Link, M. P., Zapotocky, M., Ghalibafian, M., Shaheen, N., Mushtaq, N., Waespe, N., Hijiya, N., Fuentes-Bolanos, N., Ahmad, O., Chamdine, O., Roy, P., Pichurin, P. N., Nyman, P., Pearlman, R., Auer, R. C., Sukumaran, R. K., Kebudi, R., Dvir, R., Raphael, R., Elhasid, R., McGee, R. B., Chami, R., Noss, R., Tanaka, R., Raskin, S., Sen, S., Lindhorst, S., Perreault, S., Caspi, S., Riaz, S., Constantini, S., Albert, S., Chaleff, S., Bielack, S., Chiaravalli, S., Cramer, S. L., Roy, S., Cahn, S., Penna, S., Hamid, S. A., Ghafoor, T., Imam, U., Larouche, V., Magimairajan Issai, V., Foulkes, W. D., Lee, Y. Y., Nathan, P. C., Maruvka, Y. E., Greer, M. L. C., Durno, C., Shlien, A., Ertl-Wagner, B., Villani, A., Malkin, D., Hawkins, C., Bouffet, E., Das, A. & Tabori, U., May 2024, In: The Lancet Oncology. 25, 5, p. 668-682 15 p.
Upstate Medical University
Research output: Contribution to journal › Article › peer-review

Open Access
54 Scopus citations
Multi-institution analysis of tumor mutational burden and outcomes in pediatric central nervous system tumor patients
Parisi, R., Patel, R. R., Rood, G., Bowden, A., Turco, G., Korones, D. N., Andolina, J. R., Comito, M., Barth, M. & Weintraub, L., Mar 2023, In: Pediatric Blood and Cancer. 70, 3, e30139.
University at Buffalo, Upstate Medical University
Research output: Contribution to journal › Article › peer-review
5 Scopus citations
The impacts of total body irradiation on umbilical cord blood hematopoietic stem cell transplantation
Wang, H., Berger, K. N., Miller, E. L., Fu, W., Broglie, L., Goldman, F. D., Konig, H., Lim, S. J., Berg, A. S., Talano, J. A., Comito, M. A., Farag, S. S. & Pu, J. J., Jan 1 2023, In: Therapeutic Advances in Hematology. 14
Upstate Medical University
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Successful Bone Marrow Transplantation with Intensive Post-transplant Intrathecal Chemotherapy for CNS Relapsed AML in 2 Infants
Andolina, J. R., Fries, C., Boulware, R., Vargas, A., Fraint, E., Barth, M., Ambrusko, S., Comito, M. & Monteleone, P., Jan 1 2022, In: Journal of Pediatric Hematology/Oncology. 44, 1, p. E264-E267
Upstate Medical University, University at Buffalo
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Excellent outcome of young children with nodular desmoplastic medulloblastoma treated on "head Start" III: A multi-institutional, prospective clinical trial
Dhall, G., O'Neil, S. H., Ji, L., Haley, K., Whitaker, A. M., Nelson, M. D., Gilles, F., Gardner, S. L., Allen, J. C., Cornelius, A. S., Pradhan, K., Garvin, J. H., Olshefski, R. S., Hukin, J., Comito, M., Goldman, S., Atlas, M. P., Walter, A. W., Sands, S. & Sposto, R. & 1 others, Finlay, J. L., Dec 1 2020, In: Neuro-Oncology. 22, 12, p. 1862-1872 11 p.
Upstate Medical University
Research output: Contribution to journal › Article › peer-review

Open Access
78 Scopus citations

Melanie Comito

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Collaborations and top research areas from the last five years

Dive into details

A phase 3 randomized trial of inotuzumab ozomagicin

A phase 3 randomized study of selumetinib versus carboplatin/vincristine in newly diagnosed or previously untreated neurofibromatosis type i associated low grade glioma

An open label feasibility study to assess the safety and pharmacokinetics of enasidenib in pediaric patients with relapsed/refractory acute myeloid leukemia R/R-AML with an isocitrate ehydrogenzse 2IDH1 mutation

A5481092: A phase 2 study to evaluate the safety and pharfmacokinetics of palbociclib (IBRANCE) in combination with irinotecan and temozolomide in pediatric patients with recurrent or refractory solid tumors

ACCL2031-A phase 3 randomized placebo controlled trial evaluationg memantine for neurocognitive protection in children undergoing cranial radiotherapy as part of treatment for primary central nervous system tumorw

Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study

Multi-institution analysis of tumor mutational burden and outcomes in pediatric central nervous system tumor patients

The impacts of total body irradiation on umbilical cord blood hematopoietic stem cell transplantation

Successful Bone Marrow Transplantation with Intensive Post-transplant Intrathecal Chemotherapy for CNS Relapsed AML in 2 Infants

Excellent outcome of young children with nodular desmoplastic medulloblastoma treated on "head Start" III: A multi-institutional, prospective clinical trial

Melanie Comito

Fingerprint

Collaborations and top research areas from the last five years

Grants & Projects

Research output