Personal profile
Research interests
- Artificial intelligence
- Machine learning
- Bioinformatics and computational genomics
Biography
Nancy Guo is a Professor of Empire Innovation at the School of Computing at Binghamton University's Thomas J. Watson College of Engineering and Applied Science.
Guo is experienced in leading foundation AI-based multidisciplinary research as PI of two NIH R01s and two NSF grants. She obtained more than $45.5 million in federal funding as PI/PD to develop technology and infrastructure to advance precision medicine.
She has 61 peer-reviewed journal publications with more than 3,800 citations. Her research has generated 14 patents on cancer drugs and molecular diagnostic assays with FDA “novel technology” status. Software products developed by her team have more than 46,000 visits.
As the founding director of the Biomedical Informatics Resources Core of West Virginia Clinical & Translational Science Institute from 2009-17, she led statewide informatics initiatives and enhanced multi-state collaboration. She is fostering academic-industry partnerships for clinical commercialization of AI-based cancer treatment selection and drug development through her current NSF PFI-RP project. She mentored 48 postdocs, MDs and graduate students to strive as next-generation researchers, tenured faculty, entrepreneurs as PI of NSF and NCI SBIRs and healthcare professionals recognized with nine national awards.
She served as chair of grant review panels of lung cancer research for the DOD and NCI.
Education/Academic qualification
Bachelor, Biochemistry and Molecular Biology, Peking University, Beijing, China
PhD, Computer and Information Science, West Virginia University
ASJC Scopus Subject Areas
- General Computer Science
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Collaborations and top research areas from the last five years
Grants & Projects
- 2 Active
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PFI-RP: Precision diagnostics for personalized cancer care: development of new drugs and selection of treatment
Guo, N. (PI)
07/3/24 → 03/31/27
Project: Research
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Binghamton Excellence in Entrepreneurship and Discovery (ART) Accelerating Research Translation
Dhakal, T. (CoI), Lugade, V. (CoI), Nikulin, A. (CoI), Tumey, L. (CoI), Dhakal, T. (CoI), Lugade, V. (CoI), Nikulin, A. (CoI), Tumey, L. (CoI), Katoch, B. (PI), Petrova, O. (PI), Cherny, K. (CoPI), Stromhaug, P. (CoPI), Kelkar, A. (CoPI), Nagaraju, K. (CoPI), Das, P. (CoI), Chen, Y. (CoI), Guo, N. (CoI) & Jain, J. (CoPI)
02/1/24 → 01/31/28
Project: Research
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ClinSegAI: A post-processing framework for superior histopathology segmentation accuracy, radiomics feature preservation, and quantitative analysis
Bhajaj, P., Nalubolu, S., Gurram, B., Srinivas, M., Choudhary, R., Dai, W., Wang, L., Jamaspishvili, T., Ding, Z. & Guo, N. L., Dec 2025, In: Computers in Biology and Medicine. 199, 111298.Upstate Medical University, Binghamton University
Research output: Contribution to journal › Article › peer-review
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Scientific figures interpreted by ChatGPT: strengths in plot recognition and limits in color perception
Wang, J., Ye, Q., Liu, L., Guo, N. L. & Hu, G., Dec 2024, In: npj Precision Oncology. 8, 1, 84.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Expression-Based Diagnosis, Treatment Selection, and Drug Development for Breast Cancer
Ye, Q., Wang, J., Ducatman, B., Raese, R. A., Rogers, J. L., Wan, Y. W., Dong, C., Padden, L., Pugacheva, E. N., Qian, Y. & Guo, N. L., Jul 2023, In: International Journal of Molecular Sciences. 24, 13, 10561.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Inferencing Bulk Tumor and Single-Cell Multi-Omics Regulatory Networks for Discovery of Biomarkers and Therapeutic Targets
Ye, Q. & Guo, N. L., Jan 2023, In: Cells. 12, 1, 101.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
MicroRNA, mRNA, and Proteomics Biomarkers and Therapeutic Targets for Improving Lung Cancer Treatment Outcomes
Ye, Q., Raese, R., Luo, D., Cao, S., Wan, Y. W., Qian, Y. & Guo, N. L., Apr 2023, In: Cancers. 15, 8, 2294.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations