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Molecular mechanisms of membrane disruption induced by early-stage aggregation of beta-amyloid peptides
Qiang, W. (PI) & Rozners, E. (CoI)
National Institute of General Medical Sciences
01/1/18 → 08/31/24
Project: Research
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Characterizations of the β-amyloid (Aβ)-membrane interaction intermediates
Kengwerere, M. K., Wang, T. & Qiang, W., 2026, (Accepted/In press) Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Structural convergence and membrane interactions of Aβ1-42 along the primary nucleation process studied by solid state NMR
Kengwerere, M. K., Kenyaga, J. M., Xiao, P., Gunaga, S. S., Scott, F. J., Wutoh-Hughes, X., Wang, J., Lum, B., Sun, Y., Mentink-Vigier, F., Wang, T. & Qiang, W., Dec 2025, In: Communications Chemistry. 8, 1, 131.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Extraction of In-Cell β-Amyloid Fibrillar Aggregates for Studying Molecular-Level Structural Propagations Using Solid-State NMR Spectroscopy
Kenyaga, J. M. & Qiang, W., Oct 15 2024, In: Biochemistry. 63, 20, p. 2557-2564 8 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Modulation of Lipid Dynamics in the β-Amyloid Aggregates Induced Membrane Fragmentation
Qiang, W., Kengewerere, M. K. & Kenyaga, J. M., Jun 13 2024, In: Journal of Physical Chemistry B. 128, 23, p. 5667-5675 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Neutron spin echo shows pHLIP is capable of retarding membrane thickness fluctuations
Scott, H. L., Burns-Casamayor, V., Dixson, A. C., Standaert, R. F., Stanley, C. B., Stingaciu, L. R., Carrillo, J. M. Y., Sumpter, B. G., Katsaras, J., Qiang, W., Heberle, F. A., Mertz, B., Ashkar, R. & Barrera, F. N., Oct 2024, In: Biochimica et Biophysica Acta - Biomembranes. 1866, 7, 184349.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations