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A case of mother and child with CANDLE syndrome: Diagnosis and subsequent treatment with baricitinib

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Abstract

Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) or proteasome-associated autoinflammatory syndrome is a rare autoinflammatory disorder that typically presents in infancy with characteristic symptoms, including recurrent fever, panniculitis, and progressive lipodystrophy, among other findings. We present a case of mother and child with CANDLE syndrome. The child was eventually started on baricitinib with normalization of rash and systemic findings.

Original languageEnglish
Pages (from-to)1162-1165
Number of pages4
JournalPediatric Dermatology
Volume41
Issue number6
DOIs
StatePublished - Nov 1 2024

Keywords

  • CANDLE syndrome
  • PRAAS
  • baricitinib

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