A diffuse cutaneous lymphoma secreting a potent immunosuppressant

Raoul L. Wolf; Stephanie H. Pincus; Ezio Merler; Fred S. Rosen

doi:10.1016/0090-1229(81)90128-8

A diffuse cutaneous lymphoma secreting a potent immunosuppressant

Raoul L. Wolf
, Stephanie H. Pincus
, Ezio Merler
, Fred S. Rosen

Department of Dermatology

University at Buffalo

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We have studied an unusual cutaneous lymphoma which elaborated a potent suppressor of lymphocyte proliferative responsiveness to antigens and mitogens. This suppressor was similar in extraction and function kinetics to a previously described inhibitor, lipid supressor substance (LSS). Thin-layer chromatography revealed a band derived from the patient's tumor which cochromatographed with LSS. High concentrations of LSS were found in the patient's serum. Other lymphoid tumors tested did not release LSS. The possible significance of this finding is discussed.

Original language	English
Pages (from-to)	351-361
Number of pages	11
Journal	Clinical Immunology and Immunopathology
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/0090-1229(81)90128-8
State	Published - Mar 1981

Access to Document

10.1016/0090-1229(81)90128-8

Cite this

@article{ce7710078a054103937c0675bfe16b29,

title = "A diffuse cutaneous lymphoma secreting a potent immunosuppressant",

abstract = "We have studied an unusual cutaneous lymphoma which elaborated a potent suppressor of lymphocyte proliferative responsiveness to antigens and mitogens. This suppressor was similar in extraction and function kinetics to a previously described inhibitor, lipid supressor substance (LSS). Thin-layer chromatography revealed a band derived from the patient's tumor which cochromatographed with LSS. High concentrations of LSS were found in the patient's serum. Other lymphoid tumors tested did not release LSS. The possible significance of this finding is discussed.",

author = "Wolf, \{Raoul L.\} and Pincus, \{Stephanie H.\} and Ezio Merler and Rosen, \{Fred S.\}",

year = "1981",

month = mar,

doi = "10.1016/0090-1229(81)90128-8",

language = "English",

volume = "18",

pages = "351--361",

journal = "Clinical Immunology and Immunopathology",

issn = "0090-1229",

publisher = "Academic Press Inc.",

number = "3",

}

TY - JOUR

T1 - A diffuse cutaneous lymphoma secreting a potent immunosuppressant

AU - Wolf, Raoul L.

AU - Pincus, Stephanie H.

AU - Merler, Ezio

AU - Rosen, Fred S.

PY - 1981/3

Y1 - 1981/3

N2 - We have studied an unusual cutaneous lymphoma which elaborated a potent suppressor of lymphocyte proliferative responsiveness to antigens and mitogens. This suppressor was similar in extraction and function kinetics to a previously described inhibitor, lipid supressor substance (LSS). Thin-layer chromatography revealed a band derived from the patient's tumor which cochromatographed with LSS. High concentrations of LSS were found in the patient's serum. Other lymphoid tumors tested did not release LSS. The possible significance of this finding is discussed.

AB - We have studied an unusual cutaneous lymphoma which elaborated a potent suppressor of lymphocyte proliferative responsiveness to antigens and mitogens. This suppressor was similar in extraction and function kinetics to a previously described inhibitor, lipid supressor substance (LSS). Thin-layer chromatography revealed a band derived from the patient's tumor which cochromatographed with LSS. High concentrations of LSS were found in the patient's serum. Other lymphoid tumors tested did not release LSS. The possible significance of this finding is discussed.

UR - https://www.scopus.com/pages/publications/0019352310

U2 - 10.1016/0090-1229(81)90128-8

DO - 10.1016/0090-1229(81)90128-8

M3 - Article

C2 - 7249414

SN - 0090-1229

VL - 18

SP - 351

EP - 361

JO - Clinical Immunology and Immunopathology

JF - Clinical Immunology and Immunopathology

IS - 3

ER -

A diffuse cutaneous lymphoma secreting a potent immunosuppressant

Abstract

Access to Document

Other files and links

Fingerprint

Cite this