A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus

Daniel R. Mazori; Julianne Kleitsch; Soodeh Kabir; Laura N. Uwakwe; Sharon A. Glick

doi:10.1111/pde.15408

A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus

Daniel R. Mazori
, Julianne Kleitsch
, Soodeh Kabir
, Laura N. Uwakwe
, Sharon A. Glick

Dermatology

SUNY Downstate Health Sciences University

New York University
SUNY Downstate Health Sciences University

Research output: Contribution to journal › Article › peer-review

Abstract

Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.

Original language	English
Pages (from-to)	104-107
Number of pages	4
Journal	Pediatric Dermatology
Volume	41
Issue number	1
DOIs	https://doi.org/10.1111/pde.15408
State	Published - Jan 1 2024

Keywords

SS-A/Ro antibody
SS-B/La antibody
hemophagocytic lymphohistiocytosis
neonatal lupus erythematosus

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10.1111/pde.15408

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title = "A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus",

abstract = "Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.",

keywords = "SS-A/Ro antibody, SS-B/La antibody, hemophagocytic lymphohistiocytosis, neonatal lupus erythematosus",

author = "Mazori, \{Daniel R.\} and Julianne Kleitsch and Soodeh Kabir and Uwakwe, \{Laura N.\} and Glick, \{Sharon A.\}",

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AU - Glick, Sharon A.

PY - 2024/1/1

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N2 - Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.

AB - Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.

KW - SS-A/Ro antibody

KW - SS-B/La antibody

KW - hemophagocytic lymphohistiocytosis

KW - neonatal lupus erythematosus

UR - https://www.scopus.com/pages/publications/85169781541

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A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus

Abstract

Keywords

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