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A Paper-based Enzymatic Sensor Array for Visual Detection of Glucose Levels in Urine

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

We developed a novel glucose sensor that enabled simple visual screening of specific glucose concentrations in urine. This non-invasive glucose biosensor integrated a disposable, paper-based sensing strip and a simple amplifier circuit with a visual readout. The paper sensor consisted of five enzyme-functionalized electrodes which were individually connected to a specifically designed LED indicator circuit with a predefined threshold value regarding glucose levels. The device features (i) low-cost paper-based glucose oxidase (GOX)/poly(3,4-ethylenedioxythiophene) (PEDOT) sensing electrodes, (ii) simple signal amplification and (iii) on-site, rapid and visual detection. The sensor showed reliable, discrete visual responses for determination of five glucose levels (1, 2, 3, 4 and higher than 4 mM) in urine in less than 2 minutes. This sensor will address the limitations of conventional glucose measurements.

Original languageEnglish
Title of host publicationProceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018
PublisherIEEE Computer Society
Pages244-247
Number of pages4
ISBN (Electronic)9781538675786
DOIs
StatePublished - Jul 2 2018
Event12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018 - Waikiki Beach, United States
Duration: Dec 2 2018Dec 5 2018

Publication series

NameIEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED
Volume2018-December

Conference

Conference12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018
Country/TerritoryUnited States
CityWaikiki Beach
Period12/2/1812/5/18

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