TY - JOUR
T1 - A pediatric infectious diseases perspective of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and novel coronavirus disease 2019 (COVID-19) in children
AU - Shane, Andi L.
AU - Sato, Alice I.
AU - Kao, Carol
AU - Adler-Shohet, Felice C.
AU - Vora, Surabhi B.
AU - Auletta, Jeffery J.
AU - Nachman, Sharon
AU - Raabe, Vanessa N.
AU - Inagaki, Kengo
AU - Akinboyo, Ibukunoluwa C.
AU - Woods, Charles
AU - Alsulami, Abdulsalam O.
AU - Kainth, Mundeep K.
AU - Santos, Roberto Parulan
AU - Espinosa, Claudia M.
AU - Burns, Julianne E.
AU - Cunningham, Coleen K.
AU - Dominguez, Samuel R.
AU - Martinez, Beatriz Larru
AU - Zhu, Frank
AU - Crews, Jonathan
AU - Kitano, Taito
AU - Saiman, Lisa
AU - Kotloff, Karen
N1 - Publisher Copyright: © The Author(s) 2020. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].
PY - 2020
Y1 - 2020
N2 - Understanding the role that children play in the clinical burden and propagation of severe acute respiratory syndrome coronavirus 2, responsible for coronavirus disease 2019 (COVID-19) infections, is emerging. While the severe manifestations and acute clinical burden of COVID-19 have largely spared children compared with adults, understanding the epidemiology, clinical presentation, diagnostics, management, and prevention opportunities and the social and behavioral impacts on child health is vital. Foremost is clarifying the contribution of asymptomatic and mild infections to transmission within the household and community and the clinical and epidemiologic significance of uncommon severe post-infectious complications. Here, we summarize the current knowledge, identify resources, and outline research opportunities. Pediatric infectious diseases clinicians have a unique opportunity to advocate for the inclusion of children in epidemiological, clinical, treatment, and prevention studies to optimize their care as well as to represent children in the development of guidance and policy during pandemic response.
AB - Understanding the role that children play in the clinical burden and propagation of severe acute respiratory syndrome coronavirus 2, responsible for coronavirus disease 2019 (COVID-19) infections, is emerging. While the severe manifestations and acute clinical burden of COVID-19 have largely spared children compared with adults, understanding the epidemiology, clinical presentation, diagnostics, management, and prevention opportunities and the social and behavioral impacts on child health is vital. Foremost is clarifying the contribution of asymptomatic and mild infections to transmission within the household and community and the clinical and epidemiologic significance of uncommon severe post-infectious complications. Here, we summarize the current knowledge, identify resources, and outline research opportunities. Pediatric infectious diseases clinicians have a unique opportunity to advocate for the inclusion of children in epidemiological, clinical, treatment, and prevention studies to optimize their care as well as to represent children in the development of guidance and policy during pandemic response.
KW - COVID-19
KW - Children
KW - Novel coronavirus
KW - Pediatrics
KW - SARS-CoV-2
UR - https://www.scopus.com/pages/publications/85094654880
U2 - 10.1093/JPIDS/PIAA099
DO - 10.1093/JPIDS/PIAA099
M3 - Review article
C2 - 32840614
SN - 2048-7193
VL - 9
SP - 596
EP - 608
JO - Journal of the Pediatric Infectious Diseases Society
JF - Journal of the Pediatric Infectious Diseases Society
IS - 5
ER -