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A reconstruction algorithm for breast cancer imaging with electrical impedance tomography in mammography geometry

  • Myoung Hwan Choi
  • , Tzu Jen Kao
  • , David Isaacson
  • , Gary J. Saulnier
  • , Jonathan C. Newell
  • Kangwon National University
  • Rensselaer Polytechnic Institute

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

The conductivity and permittivity of breast tumors are known to differ significantly from those of normal breast tissues, and electrical impedance tomography (EIT) is being studied as a modality for breast cancer imaging to exploit these differences. At present, X-ray mammography is the primary standard imaging modality used for breast cancer screening in clinical practice, so it is desirable to study EIT in the geometry of mammography. This paper presents a forward model of a simplified mammography geometry and a reconstruction algorithm for breast tumor imaging using EIT techniques. The mammography geometry is modeled as a rectangular box with electrode arrays on the top and bottom planes. A forward model for the electrical impedance imaging problem is derived for a homogeneous conductivity distribution and is validated by experiment using a phantom tank. A reconstruction algorithm for breast tumor imaging based on a linearization approach and the proposed forward model is presented. It is found that the proposed reconstruction algorithm performs well in the phantom experiment, and that the locations of a 5-mm-cube metal target and a 6-mm-cube agar target could be recovered at a target depth of 15 mm using a 32 electrode system.

Original languageEnglish
Article number15
Pages (from-to)700-710
Number of pages11
JournalIEEE Transactions on Biomedical Engineering
Volume54
Issue number4
DOIs
StatePublished - Apr 2007

Keywords

  • Breast imaging
  • Electrical impedance tomography
  • Mammography geometry
  • Reconstruction algorithm

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