A retrograde gradient for disruption of a conditioned aversion to drinking cold water by ECS administered during the CS-US interval

Wesley J. Kasprow; Todd R. Schachtman; Ralph R. Miller

doi:10.1016/0031-9384(85)90007-1

A retrograde gradient for disruption of a conditioned aversion to drinking cold water by ECS administered during the CS-US interval

Wesley J. Kasprow
, Todd R. Schachtman
, Ralph R. Miller

Psychology

Binghamton University

State University of New York Binghamton University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Rats were used to examine the effects, upon a conditioned aversion to cold drinking water, of electroconvulsive shock (ECS) delivered during the delay between cue and unconditioned stimulus. An injection of LiCl (US) 30 min after ingestion of novel cold water (CS) produced a reliable aversion to the cold water. ECS given immediately following the ingestion of cold water substantially attenuated this aversion. An orderly decrease in the attenuation of the aversion was observed when ECS was delayed 5, 10 or 20 min after offset of the cold water cue. The results indicate that ingestive cue aversions can be formed without electrochemical neural-transmission-based representation of the cue being maintained during the CS-US interval. The differential effectiveness of ECS suggests that this agent retroactively interferes with processing of the ingestive cue.

Original language	English
Pages (from-to)	879-882
Number of pages	4
Journal	Physiology and Behavior
Volume	34
Issue number	6
DOIs	https://doi.org/10.1016/0031-9384(85)90007-1
State	Published - Jun 1985

Keywords

CS-US interval
Conditioned aversion
Electroconvulsive shock
Retrograde amnesia
Trace conditioning

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10.1016/0031-9384(85)90007-1

Cite this

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title = "A retrograde gradient for disruption of a conditioned aversion to drinking cold water by ECS administered during the CS-US interval",

abstract = "Rats were used to examine the effects, upon a conditioned aversion to cold drinking water, of electroconvulsive shock (ECS) delivered during the delay between cue and unconditioned stimulus. An injection of LiCl (US) 30 min after ingestion of novel cold water (CS) produced a reliable aversion to the cold water. ECS given immediately following the ingestion of cold water substantially attenuated this aversion. An orderly decrease in the attenuation of the aversion was observed when ECS was delayed 5, 10 or 20 min after offset of the cold water cue. The results indicate that ingestive cue aversions can be formed without electrochemical neural-transmission-based representation of the cue being maintained during the CS-US interval. The differential effectiveness of ECS suggests that this agent retroactively interferes with processing of the ingestive cue.",

keywords = "CS-US interval, Conditioned aversion, Electroconvulsive shock, Retrograde amnesia, Trace conditioning",

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T1 - A retrograde gradient for disruption of a conditioned aversion to drinking cold water by ECS administered during the CS-US interval

AU - Kasprow, Wesley J.

AU - Schachtman, Todd R.

AU - Miller, Ralph R.

PY - 1985/6

Y1 - 1985/6

N2 - Rats were used to examine the effects, upon a conditioned aversion to cold drinking water, of electroconvulsive shock (ECS) delivered during the delay between cue and unconditioned stimulus. An injection of LiCl (US) 30 min after ingestion of novel cold water (CS) produced a reliable aversion to the cold water. ECS given immediately following the ingestion of cold water substantially attenuated this aversion. An orderly decrease in the attenuation of the aversion was observed when ECS was delayed 5, 10 or 20 min after offset of the cold water cue. The results indicate that ingestive cue aversions can be formed without electrochemical neural-transmission-based representation of the cue being maintained during the CS-US interval. The differential effectiveness of ECS suggests that this agent retroactively interferes with processing of the ingestive cue.

AB - Rats were used to examine the effects, upon a conditioned aversion to cold drinking water, of electroconvulsive shock (ECS) delivered during the delay between cue and unconditioned stimulus. An injection of LiCl (US) 30 min after ingestion of novel cold water (CS) produced a reliable aversion to the cold water. ECS given immediately following the ingestion of cold water substantially attenuated this aversion. An orderly decrease in the attenuation of the aversion was observed when ECS was delayed 5, 10 or 20 min after offset of the cold water cue. The results indicate that ingestive cue aversions can be formed without electrochemical neural-transmission-based representation of the cue being maintained during the CS-US interval. The differential effectiveness of ECS suggests that this agent retroactively interferes with processing of the ingestive cue.

KW - CS-US interval

KW - Conditioned aversion

KW - Electroconvulsive shock

KW - Retrograde amnesia

KW - Trace conditioning

UR - https://www.scopus.com/pages/publications/0022348871

U2 - 10.1016/0031-9384(85)90007-1

DO - 10.1016/0031-9384(85)90007-1

M3 - Article

C2 - 2997815

SN - 0031-9384

VL - 34

SP - 879

EP - 882

JO - Physiology and Behavior

JF - Physiology and Behavior

IS - 6

ER -

A retrograde gradient for disruption of a conditioned aversion to drinking cold water by ECS administered during the CS-US interval

Abstract

Keywords

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