@inproceedings{e1bc18bc36aa452189b27654a1571ac8,
title = "A stochastic model of proliferation of cancer stem cells and its estimation by particle filtering",
abstract = "In this paper, we propose a model for proliferation of cancer stem cells and a procedure for estimating the unknowns of the model. Understanding the proliferation of cancer stem cells is critical for the development of anti-cancer therapies. We propose to use a non-linear and non-Gaussian state-space model for studying the proliferation process. For estimation of the unknowns we apply particle filtering, which is particularly appropriate given the nature of the model. In addition, we deal with a very large dimension of the state-space and very sparse time series of measurements. Computer simulations show promising results in a simple scenario generated with synthetic data.",
keywords = "Cancer stem cells, High dimensional systems, Particle filtering, Sparse time series",
author = "Bugallo, \{M{\'o}nica F.\} and Galina Botchkina and Djuri{\'c}, \{Petar M.\}",
year = "2010",
doi = "10.1109/ICASSP.2010.5495634",
language = "English",
isbn = "9781424442966",
series = "ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "529--533",
booktitle = "2010 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2010 - Proceedings",
note = "2010 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2010 ; Conference date: 14-03-2010 Through 19-03-2010",
}