A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip

Kwang W. Oh; Chinsung Park; Kak Namkoong

doi:10.1109/MEMSYS.2005.1454029

A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip

Kwang W. Oh
, Chinsung Park
, Kak Namkoong

Department of Electrical Engineering

University at Buffalo

Samsung

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

14 Scopus citations

Abstract

This paper presents a practical world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber Micro PCR (Polymerase Chain Reaction) chip. After sample injection and sealing, leakage test is conducted by elevating the temperature upto 100°C for 30 min. No leakage flows are found during the test for 10 cartridges. In conclusion, we have introduced a simple and cheap microfluidic interconnection technology for both sample injection and sealing, which provides a zero dead volume, a zero leakage flow, and biochemical compatibility. Also, this world-to-chip interconnection technology enables one or more operators to interface between the micro world and real world easily by using conventional pipettes.

Original language	English
Title of host publication	Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest
Pages	714-717
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2005.1454029
State	Published - 2005
Event	18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Miami Beach, FL, United States Duration: Jan 30 2005 → Feb 3 2005

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

Conference

Conference	18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami
Country/Territory	United States
City	Miami Beach, FL
Period	01/30/05 → 02/3/05

Access to Document

10.1109/MEMSYS.2005.1454029

Cite this

Oh, K. W., Park, C., & Namkoong, K. (2005). A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. In Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest (pp. 714-717). Article WP14 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2005.1454029

Oh, Kwang W. ; Park, Chinsung ; Namkoong, Kak. / A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest. 2005. pp. 714-717 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

@inproceedings{8f1a7fdee9c54f6494909c6cfebef04c,

title = "A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip",

abstract = "This paper presents a practical world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber Micro PCR (Polymerase Chain Reaction) chip. After sample injection and sealing, leakage test is conducted by elevating the temperature upto 100°C for 30 min. No leakage flows are found during the test for 10 cartridges. In conclusion, we have introduced a simple and cheap microfluidic interconnection technology for both sample injection and sealing, which provides a zero dead volume, a zero leakage flow, and biochemical compatibility. Also, this world-to-chip interconnection technology enables one or more operators to interface between the micro world and real world easily by using conventional pipettes.",

author = "Oh, \{Kwang W.\} and Chinsung Park and Kak Namkoong",

year = "2005",

doi = "10.1109/MEMSYS.2005.1454029",

language = "English",

isbn = "0780387325",

series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

pages = "714--717",

booktitle = "Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest",

note = "18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami ; Conference date: 30-01-2005 Through 03-02-2005",

}

Oh, KW, Park, C & Namkoong, K 2005, A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. in Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest., WP14, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 714-717, 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami, Miami Beach, FL, United States, 01/30/05. https://doi.org/10.1109/MEMSYS.2005.1454029

A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. / Oh, Kwang W.; Park, Chinsung; Namkoong, Kak.
Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest. 2005. p. 714-717 WP14 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip

AU - Oh, Kwang W.

AU - Park, Chinsung

AU - Namkoong, Kak

PY - 2005

Y1 - 2005

N2 - This paper presents a practical world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber Micro PCR (Polymerase Chain Reaction) chip. After sample injection and sealing, leakage test is conducted by elevating the temperature upto 100°C for 30 min. No leakage flows are found during the test for 10 cartridges. In conclusion, we have introduced a simple and cheap microfluidic interconnection technology for both sample injection and sealing, which provides a zero dead volume, a zero leakage flow, and biochemical compatibility. Also, this world-to-chip interconnection technology enables one or more operators to interface between the micro world and real world easily by using conventional pipettes.

AB - This paper presents a practical world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber Micro PCR (Polymerase Chain Reaction) chip. After sample injection and sealing, leakage test is conducted by elevating the temperature upto 100°C for 30 min. No leakage flows are found during the test for 10 cartridges. In conclusion, we have introduced a simple and cheap microfluidic interconnection technology for both sample injection and sealing, which provides a zero dead volume, a zero leakage flow, and biochemical compatibility. Also, this world-to-chip interconnection technology enables one or more operators to interface between the micro world and real world easily by using conventional pipettes.

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DO - 10.1109/MEMSYS.2005.1454029

M3 - Conference contribution

SN - 0780387325

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

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EP - 717

BT - Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest

T2 - 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami

Y2 - 30 January 2005 through 3 February 2005

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Oh KW, Park C, Namkoong K. A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. In Proceedings of the 18th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2005 Miami - Technical Digest. 2005. p. 714-717. WP14. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2005.1454029

A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip

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