Activation-blood flow coupling during direct somatosensory cortical stimulation in living rat brain

Zhongchi Luo; Helene Benveniste; Mei Yu; Congwu Du

doi:10.1109/CNE.2005.1419712

Activation-blood flow coupling during direct somatosensory cortical stimulation in living rat brain

Zhongchi Luo
, Helene Benveniste
, Mei Yu
, Congwu Du

Dept of Biomedical Engineering

Stony Brook University

Brookhaven National Laboratory
Stony Brook University

Research output: Contribution to conference › Paper › peer-review

Abstract

Laser Doppler flowmetry was used to characterize the cortical activation-blood flow coupling due to direct stimulation in somatosensory cortex of rat brain in vivo. Both amplitude and duration of the flow response increased along with the increases in stimulation current. Flow response became to saturate in a high-grade stimulation with the current above 0.3 mA. The flow response also featured a fast activation due to the stimulus and a slow recovery, which may imply an indirect coupling between neural activity and recruitment of local blood delivery.

Original language	English
Pages	664-666
Number of pages	3
DOIs	https://doi.org/10.1109/CNE.2005.1419712
State	Published - 2005
Event	2nd International IEEE EMBS Conference on Neural Engineering, 2005 - Arlington, VA, United States Duration: Mar 16 2005 → Mar 19 2005

Conference

Conference	2nd International IEEE EMBS Conference on Neural Engineering, 2005
Country/Territory	United States
City	Arlington, VA
Period	03/16/05 → 03/19/05

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10.1109/CNE.2005.1419712

Cite this

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title = "Activation-blood flow coupling during direct somatosensory cortical stimulation in living rat brain",

abstract = "Laser Doppler flowmetry was used to characterize the cortical activation-blood flow coupling due to direct stimulation in somatosensory cortex of rat brain in vivo. Both amplitude and duration of the flow response increased along with the increases in stimulation current. Flow response became to saturate in a high-grade stimulation with the current above 0.3 mA. The flow response also featured a fast activation due to the stimulus and a slow recovery, which may imply an indirect coupling between neural activity and recruitment of local blood delivery.",

author = "Zhongchi Luo and Helene Benveniste and Mei Yu and Congwu Du",

year = "2005",

doi = "10.1109/CNE.2005.1419712",

language = "English",

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note = "2nd International IEEE EMBS Conference on Neural Engineering, 2005 ; Conference date: 16-03-2005 Through 19-03-2005",

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T1 - Activation-blood flow coupling during direct somatosensory cortical stimulation in living rat brain

AU - Luo, Zhongchi

AU - Benveniste, Helene

AU - Yu, Mei

AU - Du, Congwu

PY - 2005

Y1 - 2005

N2 - Laser Doppler flowmetry was used to characterize the cortical activation-blood flow coupling due to direct stimulation in somatosensory cortex of rat brain in vivo. Both amplitude and duration of the flow response increased along with the increases in stimulation current. Flow response became to saturate in a high-grade stimulation with the current above 0.3 mA. The flow response also featured a fast activation due to the stimulus and a slow recovery, which may imply an indirect coupling between neural activity and recruitment of local blood delivery.

AB - Laser Doppler flowmetry was used to characterize the cortical activation-blood flow coupling due to direct stimulation in somatosensory cortex of rat brain in vivo. Both amplitude and duration of the flow response increased along with the increases in stimulation current. Flow response became to saturate in a high-grade stimulation with the current above 0.3 mA. The flow response also featured a fast activation due to the stimulus and a slow recovery, which may imply an indirect coupling between neural activity and recruitment of local blood delivery.

UR - https://www.scopus.com/pages/publications/33744496786

U2 - 10.1109/CNE.2005.1419712

DO - 10.1109/CNE.2005.1419712

M3 - Paper

SP - 664

EP - 666

T2 - 2nd International IEEE EMBS Conference on Neural Engineering, 2005

Y2 - 16 March 2005 through 19 March 2005

ER -

Activation-blood flow coupling during direct somatosensory cortical stimulation in living rat brain

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