Agents of Actinomycosis

Thomas A. Russo

doi:10.1016/B978-0-323-48255-4.00254-X

Agents of Actinomycosis

Thomas A. Russo

Medicine

University at Buffalo

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

Abstract

Actinomycosis, a chronic indolent infection, can involve any site in the body and is a diagnostic challenge that requires knowledge of the full spectrum of clinical syndromes. Three classic presentations that should prompt consideration of this unique infection are (1) chronicity, progression across tissue boundaries, and masslike features (mimicking malignancy, with which it is often confused); (2) the development of a sinus tract; and (3) a refractory or relapsing infection after a short course of therapy, because cure of established actinomycosis requires prolonged treatment. Recognition is critical to expedite diagnosis and treatment, and to minimize unnecessary surgical interventions, morbidity, and mortality.

Original language	English
Title of host publication	Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 9th Edition
Subtitle of host publication	Volume 1-2
Publisher	Elsevier
Pages	3071-3081.e3
Volume	2
ISBN (Electronic)	9780323482554
ISBN (Print)	9780323775564
DOIs	https://doi.org/10.1016/B978-0-323-48255-4.00254-X
State	Published - Jan 1 2019

Keywords

Actinomyces
actinomycosis
bisphosphonate-associated infection
companion organisms
filamentous rods
intrauterine device-associated infection
malignancy mimic
relapsing infection
sinus tract
sulfur granule

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10.1016/B978-0-323-48255-4.00254-X

Cite this

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title = "Agents of Actinomycosis",

abstract = "Actinomycosis, a chronic indolent infection, can involve any site in the body and is a diagnostic challenge that requires knowledge of the full spectrum of clinical syndromes. Three classic presentations that should prompt consideration of this unique infection are (1) chronicity, progression across tissue boundaries, and masslike features (mimicking malignancy, with which it is often confused); (2) the development of a sinus tract; and (3) a refractory or relapsing infection after a short course of therapy, because cure of established actinomycosis requires prolonged treatment. Recognition is critical to expedite diagnosis and treatment, and to minimize unnecessary surgical interventions, morbidity, and mortality.",

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T1 - Agents of Actinomycosis

AU - Russo, Thomas A.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Actinomycosis, a chronic indolent infection, can involve any site in the body and is a diagnostic challenge that requires knowledge of the full spectrum of clinical syndromes. Three classic presentations that should prompt consideration of this unique infection are (1) chronicity, progression across tissue boundaries, and masslike features (mimicking malignancy, with which it is often confused); (2) the development of a sinus tract; and (3) a refractory or relapsing infection after a short course of therapy, because cure of established actinomycosis requires prolonged treatment. Recognition is critical to expedite diagnosis and treatment, and to minimize unnecessary surgical interventions, morbidity, and mortality.

AB - Actinomycosis, a chronic indolent infection, can involve any site in the body and is a diagnostic challenge that requires knowledge of the full spectrum of clinical syndromes. Three classic presentations that should prompt consideration of this unique infection are (1) chronicity, progression across tissue boundaries, and masslike features (mimicking malignancy, with which it is often confused); (2) the development of a sinus tract; and (3) a refractory or relapsing infection after a short course of therapy, because cure of established actinomycosis requires prolonged treatment. Recognition is critical to expedite diagnosis and treatment, and to minimize unnecessary surgical interventions, morbidity, and mortality.

KW - Actinomyces

KW - actinomycosis

KW - bisphosphonate-associated infection

KW - companion organisms

KW - filamentous rods

KW - intrauterine device-associated infection

KW - malignancy mimic

KW - relapsing infection

KW - sinus tract

KW - sulfur granule

UR - https://www.scopus.com/pages/publications/105001412883

U2 - 10.1016/B978-0-323-48255-4.00254-X

DO - 10.1016/B978-0-323-48255-4.00254-X

M3 - Chapter

SN - 9780323775564

VL - 2

SP - 3071-3081.e3

BT - Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 9th Edition

PB - Elsevier

ER -

Agents of Actinomycosis

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Keywords

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