Alzheimer's disease in a patient on long-term hemodialysis: A case report

B. Trappler; R. Viswanathan; J. Sher

doi:10.1016/0163-8343(86)90065-4

Alzheimer's disease in a patient on long-term hemodialysis: A case report

B. Trappler
, R. Viswanathan
, J. Sher

Psychiatry

SUNY Downstate Health Sciences University

SUNY Downstate Health Sciences University

Research output: Contribution to journal › Article › peer-review

Abstract

This case report describes a progressive dementia in a 49-year-old black male on long-term hemodialysis. The initial presentation simulated depression. The dementia persisted after an unsuccessful cadaver homograft transplant. The character of the dementia was nonspecific but typical features of dialysis dementia were lacking. Autopsy revealed a ruptured cerebral aneurysm, polycystic kidneys, moderately severe atherosclerosis, miliary tuberculosis, and neurofibrillary degeneration of the hippocampus. The significance of a possible relationship between end-stage renal disease (ESRD), hemodialysis, and Alzheimer's disease in this case is discussed.

Original language	English
Pages (from-to)	57-60
Number of pages	4
Journal	General Hospital Psychiatry
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/0163-8343(86)90065-4
State	Published - Jan 1986

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abstract = "This case report describes a progressive dementia in a 49-year-old black male on long-term hemodialysis. The initial presentation simulated depression. The dementia persisted after an unsuccessful cadaver homograft transplant. The character of the dementia was nonspecific but typical features of dialysis dementia were lacking. Autopsy revealed a ruptured cerebral aneurysm, polycystic kidneys, moderately severe atherosclerosis, miliary tuberculosis, and neurofibrillary degeneration of the hippocampus. The significance of a possible relationship between end-stage renal disease (ESRD), hemodialysis, and Alzheimer's disease in this case is discussed.",

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AB - This case report describes a progressive dementia in a 49-year-old black male on long-term hemodialysis. The initial presentation simulated depression. The dementia persisted after an unsuccessful cadaver homograft transplant. The character of the dementia was nonspecific but typical features of dialysis dementia were lacking. Autopsy revealed a ruptured cerebral aneurysm, polycystic kidneys, moderately severe atherosclerosis, miliary tuberculosis, and neurofibrillary degeneration of the hippocampus. The significance of a possible relationship between end-stage renal disease (ESRD), hemodialysis, and Alzheimer's disease in this case is discussed.

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Alzheimer's disease in a patient on long-term hemodialysis: A case report

Abstract

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