Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.

S. David Kimball; K. S. Kim; Dillip K. Mohanty; Ermes Vanotti; Francis Johnson

doi:10.1016/S0040-4039(00)87730-8

Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.

S. David Kimball
, K. S. Kim
, Dillip K. Mohanty
, Ermes Vanotti
, Francis Johnson

Pharmacological Sciences

Stony Brook University

Stony Brook University

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Daunomycinone 2a has been synthesized by a novel regio- and stereoselective route that establishes the tetracyclic framework and the C-7 oxygen in naphthacenol 5c via a double Friedel-Crafts acylation.

Original language	English
Pages (from-to)	3871-3874
Number of pages	4
Journal	Tetrahedron Letters
Volume	23
Issue number	38
DOIs	https://doi.org/10.1016/S0040-4039(00)87730-8
State	Published - 1982

Access to Document

10.1016/S0040-4039(00)87730-8

Cite this

@article{c035dc728bb54c0696c152c0c7190500,

title = "Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.",

abstract = "Daunomycinone 2a has been synthesized by a novel regio- and stereoselective route that establishes the tetracyclic framework and the C-7 oxygen in naphthacenol 5c via a double Friedel-Crafts acylation.",

author = "Kimball, \{S. David\} and Kim, \{K. S.\} and Mohanty, \{Dillip K.\} and Ermes Vanotti and Francis Johnson",

year = "1982",

doi = "10.1016/S0040-4039(00)87730-8",

language = "English",

volume = "23",

pages = "3871--3874",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "38",

}

TY - JOUR

T1 - Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.

AU - Kimball, S. David

AU - Kim, K. S.

AU - Mohanty, Dillip K.

AU - Vanotti, Ermes

AU - Johnson, Francis

PY - 1982

Y1 - 1982

N2 - Daunomycinone 2a has been synthesized by a novel regio- and stereoselective route that establishes the tetracyclic framework and the C-7 oxygen in naphthacenol 5c via a double Friedel-Crafts acylation.

AB - Daunomycinone 2a has been synthesized by a novel regio- and stereoselective route that establishes the tetracyclic framework and the C-7 oxygen in naphthacenol 5c via a double Friedel-Crafts acylation.

UR - https://www.scopus.com/pages/publications/0020465581

U2 - 10.1016/S0040-4039(00)87730-8

DO - 10.1016/S0040-4039(00)87730-8

M3 - Article

SN - 0040-4039

VL - 23

SP - 3871

EP - 3874

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 38

ER -

Anthracyclines and related substances. 4. A novel regio- and stereoselective total synthesis of 7-epidaunomycinone and daunomycinone.

Abstract

Access to Document

Other files and links

Fingerprint

Cite this