Benzaldehyde-functionalized polymer vesicles

Guorong Sun; Huafeng Fang; Chong Cheng; Peng Lu; Ke Zhang; Amy V. Walker; John Stephen A. Taylor; Karen L. Wooley

doi:10.1021/nn8007977

Benzaldehyde-functionalized polymer vesicles

Guorong Sun
, Huafeng Fang
, Chong Cheng
, Peng Lu
, Ke Zhang
, Amy V. Walker
, John Stephen A. Taylor
, Karen L. Wooley

Department of Chemical and Biological Engineering

University at Buffalo

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

Polymer vesicles with diameters of ca. 100-600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO ₄₅-b- PVBA26 in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.

Original language	English
Pages (from-to)	673-681
Number of pages	9
Journal	ACS Nano
Volume	3
Issue number	3
DOIs	https://doi.org/10.1021/nn8007977
State	Published - Mar 24 2009

Keywords

Amphiphilic block copolymers
Reactive polymers
Vesicular nanostructures

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10.1021/nn8007977

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title = "Benzaldehyde-functionalized polymer vesicles",

abstract = "Polymer vesicles with diameters of ca. 100-600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO 45-b- PVBA26 in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.",

keywords = "Amphiphilic block copolymers, Reactive polymers, Vesicular nanostructures",

author = "Guorong Sun and Huafeng Fang and Chong Cheng and Peng Lu and Ke Zhang and Walker, \{Amy V.\} and Taylor, \{John Stephen A.\} and Wooley, \{Karen L.\}",

year = "2009",

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day = "24",

doi = "10.1021/nn8007977",

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journal = "ACS Nano",

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T1 - Benzaldehyde-functionalized polymer vesicles

AU - Sun, Guorong

AU - Fang, Huafeng

AU - Cheng, Chong

AU - Lu, Peng

AU - Zhang, Ke

AU - Walker, Amy V.

AU - Taylor, John Stephen A.

AU - Wooley, Karen L.

PY - 2009/3/24

Y1 - 2009/3/24

N2 - Polymer vesicles with diameters of ca. 100-600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO 45-b- PVBA26 in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.

AB - Polymer vesicles with diameters of ca. 100-600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO 45-b- PVBA26 in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association.

KW - Amphiphilic block copolymers

KW - Reactive polymers

KW - Vesicular nanostructures

UR - https://www.scopus.com/pages/publications/63649147836

U2 - 10.1021/nn8007977

DO - 10.1021/nn8007977

M3 - Article

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VL - 3

SP - 673

EP - 681

JO - ACS Nano

JF - ACS Nano

IS - 3

ER -

Benzaldehyde-functionalized polymer vesicles

Abstract

Keywords

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