Chapter 2: Gadolinium-based Contrast Agents

Lothar Helm; Janet R. Morrow; Christopher J. Bond; Fabio Carniato; Mauro Botta; Mihály Braun; Zsolt Baranyai; Rosa Pujales-Paradela; Martín Regueiro-Figueroa; David Esteban-Gómez; Carlos Platas-Iglesias; Timothy J. Scholl

doi:10.1039/9781788010146-00121

Chapter 2: Gadolinium-based Contrast Agents

Lothar Helm
, Janet R. Morrow
, Christopher J. Bond
, Fabio Carniato
, Mauro Botta
, Mihály Braun
, Zsolt Baranyai
, Rosa Pujales-Paradela
, Martín Regueiro-Figueroa
, David Esteban-Gómez
, Carlos Platas-Iglesias
, Timothy J. Scholl

Chemistry

University at Buffalo

Swiss Federal Institute of Technology Lausanne
SUNY Buffalo
University of Eastern Piedmont
Hungarian Academy of Sciences
University of Debrecen
University of A Coruna
Western University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

29 Scopus citations

Abstract

In this chapter, the development of efficient Gd^III-based agents for MRI is detailed. This chapter is divided into ten sections covering the general theory of the relaxivity of Gd^III-based contrast agents; the measurement of longitudinal (T₁) and transverse (T₂) relaxation times; the theory, acquisition, and interpretation of NMRD profiles; the determination of water-coordination numbers (q), rotational-correlation times (τ_R), water-residence times (τ_M), and concentrations of solutions of Gd^III complexes; as well as relaxometric titrations, computational methods, and the acquisition of phantom images.

Original language	English
Title of host publication	New Developments in NMR
Editors	Valerie C. Pierre, Matthew J. Allen
Publisher	Royal Society of Chemistry
Pages	121-242
Number of pages	122
Edition	13
ISBN (Electronic)	9781782624479, 9781782628545, 9781849736435, 9781849739139
ISBN (Print)	9781788010863, 9781788011044
DOIs	https://doi.org/10.1039/9781788010146-00121
State	Published - 2018

Publication series

Name	New Developments in NMR
Number	13
Volume	2018-January

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10.1039/9781788010146-00121

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Helm, L., Morrow, J. R., Bond, C. J., Carniato, F., Botta, M., Braun, M., Baranyai, Z., Pujales-Paradela, R., Regueiro-Figueroa, M., Esteban-Gómez, D., Platas-Iglesias, C., & Scholl, T. J. (2018). Chapter 2: Gadolinium-based Contrast Agents. In V. C. Pierre, & M. J. Allen (Eds.), New Developments in NMR (13 ed., pp. 121-242). (New Developments in NMR; Vol. 2018-January, No. 13). Royal Society of Chemistry. https://doi.org/10.1039/9781788010146-00121

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title = "Chapter 2: Gadolinium-based Contrast Agents",

abstract = "In this chapter, the development of efficient GdIII-based agents for MRI is detailed. This chapter is divided into ten sections covering the general theory of the relaxivity of GdIII-based contrast agents; the measurement of longitudinal (T1) and transverse (T2) relaxation times; the theory, acquisition, and interpretation of NMRD profiles; the determination of water-coordination numbers (q), rotational-correlation times (τR), water-residence times (τM), and concentrations of solutions of GdIII complexes; as well as relaxometric titrations, computational methods, and the acquisition of phantom images.",

author = "Lothar Helm and Morrow, \{Janet R.\} and Bond, \{Christopher J.\} and Fabio Carniato and Mauro Botta and Mih{\'a}ly Braun and Zsolt Baranyai and Rosa Pujales-Paradela and Mart{\'i}n Regueiro-Figueroa and David Esteban-G{\'o}mez and Carlos Platas-Iglesias and Scholl, \{Timothy J.\}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2018.",

year = "2018",

doi = "10.1039/9781788010146-00121",

language = "English",

isbn = "9781788010863",

series = "New Developments in NMR",

publisher = "Royal Society of Chemistry",

number = "13",

pages = "121--242",

editor = "Pierre, \{Valerie C.\} and Allen, \{Matthew J.\}",

booktitle = "New Developments in NMR",

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Helm, L, Morrow, JR, Bond, CJ, Carniato, F, Botta, M, Braun, M, Baranyai, Z, Pujales-Paradela, R, Regueiro-Figueroa, M, Esteban-Gómez, D, Platas-Iglesias, C & Scholl, TJ 2018, Chapter 2: Gadolinium-based Contrast Agents. in VC Pierre & MJ Allen (eds), New Developments in NMR. 13 edn, New Developments in NMR, no. 13, vol. 2018-January, Royal Society of Chemistry, pp. 121-242. https://doi.org/10.1039/9781788010146-00121

Chapter 2: Gadolinium-based Contrast Agents. / Helm, Lothar; Morrow, Janet R.; Bond, Christopher J. et al.
New Developments in NMR. ed. / Valerie C. Pierre; Matthew J. Allen. 13. ed. Royal Society of Chemistry, 2018. p. 121-242 (New Developments in NMR; Vol. 2018-January, No. 13).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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AU - Platas-Iglesias, Carlos

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A2 - Pierre, Valerie C.

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ER -

Chapter 2: Gadolinium-based Contrast Agents

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