Coadministration of fluvoxamine increases serum concentrations of haloperidol

David G. Daniel; Chris Randolph; George Jaskiw; Sharon Handel; Tracy Williams; Annissa Abi-Dargham; Susan Shoaf; Michel Egan; Ahmed Elkashef; Stephanie Liboff; Markku Linnoila

Coadministration of fluvoxamine increases serum concentrations of haloperidol

David G. Daniel
, Chris Randolph
, George Jaskiw
, Sharon Handel
, Tracy Williams
, Annissa Abi-Dargham
, Susan Shoaf
, Michel Egan
, Ahmed Elkashef
, Stephanie Liboff
, Markku Linnoila

Psychiatry

Stony Brook University

National Institutes of Health
Washington Clinical Research Center

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.

Original language	English
Pages (from-to)	340-343
Number of pages	4
Journal	Journal of Clinical Psychopharmacology
Volume	14
Issue number	5
State	Published - Oct 1994

Cite this

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title = "Coadministration of fluvoxamine increases serum concentrations of haloperidol",

abstract = "Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.",

author = "Daniel, \{David G.\} and Chris Randolph and George Jaskiw and Sharon Handel and Tracy Williams and Annissa Abi-Dargham and Susan Shoaf and Michel Egan and Ahmed Elkashef and Stephanie Liboff and Markku Linnoila",

year = "1994",

month = oct,

language = "English",

volume = "14",

pages = "340--343",

journal = "Journal of Clinical Psychopharmacology",

issn = "0271-0749",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Coadministration of fluvoxamine increases serum concentrations of haloperidol

AU - Daniel, David G.

AU - Randolph, Chris

AU - Jaskiw, George

AU - Handel, Sharon

AU - Williams, Tracy

AU - Abi-Dargham, Annissa

AU - Shoaf, Susan

AU - Egan, Michel

AU - Elkashef, Ahmed

AU - Liboff, Stephanie

AU - Linnoila, Markku

PY - 1994/10

Y1 - 1994/10

N2 - Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.

AB - Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.

UR - https://www.scopus.com/pages/publications/0028150994

M3 - Article

C2 - 7806690

SN - 0271-0749

VL - 14

SP - 340

EP - 343

JO - Journal of Clinical Psychopharmacology

JF - Journal of Clinical Psychopharmacology

IS - 5

ER -

Coadministration of fluvoxamine increases serum concentrations of haloperidol

Abstract

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