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Consistency of the generalized MLE of a joint distribution function with multivariate interval-censored data

  • Novartis
  • Strang Cancer Prevention Center

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Wong and Yu [Generalized MLE of a joint distribution function with multivariate interval-censored data, J. Multivariate Anal. 69 (1999) 155-166] discussed generalized maximum likelihood estimation of the joint distribution function of a multivariate random vector whose coordinates are subject to interval censoring. They established uniform consistency of the generalized MLE (GMLE) of the distribution function under the assumption that the random vector is independent of the censoring vector and that both of the vector distributions are discrete. We relax these assumptions and establish consistency results of the GMLE under a multivariate mixed case interval censorship model. van der Vaart and Wellner [Preservation theorems for Glivenko-Cantelli and uniform Glivenko-Cantelli class, in: E. Gine, D.M. Mason, J.A. Wellner (Eds.), High Dimensional Probability, vol. II, Birkhäuser, Boston, 2000, pp. 115-133] and Yu [Consistency of the generalized MLE with multivariate mixed case interval-censored data, Ph.D Dissertation, Binghamton University, 2000] independently proved strong consistency of the GMLE in the L1 (μ)-topology, where μ is a measure derived from the joint distribution of the censoring variables. We establish strong consistency of the GMLE in the topologies of weak convergence and pointwise convergence, and eventually uniform convergence under appropriate distributional assumptions and regularity conditions.

Original languageEnglish
Pages (from-to)720-732
Number of pages13
JournalJournal of Multivariate Analysis
Volume97
Issue number3
DOIs
StatePublished - Mar 2006

Keywords

  • Case k model
  • Consistency
  • General maximum likelihood estimation
  • Mixed case model
  • Multivariate interval censorship model

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