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Contrast-enhanced micro-CT imaging of soft tissues

  • Angela S.P. Lin
  • , Ashley W. Palmer
  • , Craig L. Duvall
  • , Galen C. Robertson
  • , Megan E. Oest
  • , Bina Rai
  • , Marc E. Levenston
  • , Robert E. Guldberg
  • Georgia Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Analyzing the three-dimensional (3D) structure of specimens has become increasingly important in biomedical research fields, and microcomputed tomography (micro-CT) has emerged as an effective method for rapidly and non-destructively quantifying the geometry and morphology of tissues. Though micro-CT was originally designed to assess cortical and trabecular bone microarchitecture, applications for micro-CT now extend to the imaging of soft tissues. In particular, vascular anatomy and articular cartilage degradation are of major interest to investigators in the orthopedic research areas. This chapter outlines processes and results involved in utilizing X-ray contrast agents to enhance micro-CT analyses of vasculature and articular cartilage.

Original languageEnglish
Title of host publicationAdvanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials
Subtitle of host publicationTechniques and Applications
PublisherSpringer Berlin Heidelberg
Pages239-256
Number of pages18
ISBN (Print)9783540454540
DOIs
StatePublished - 2007

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