Correlates of Psychosis Proneness in Relatives of Schizophrenic Patients

Michael J. Lyons; Rosemary Toomey; Stephen V. Faraone; William S. Kremen; Albert S. Yeung; Ming T. Tsuang

doi:10.1037/0021-843X.104.2.390

Correlates of Psychosis Proneness in Relatives of Schizophrenic Patients

Michael J. Lyons
, Rosemary Toomey
, Stephen V. Faraone
, William S. Kremen
, Albert S. Yeung
, Ming T. Tsuang

Psychiatry

Upstate Medical University

Boston University
Harvard University
VA Medical Center
Massachusetts Department of Mental Health
Massachusetts General Hospital

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The Magical Ideation Scale (MIS), Perceptual Aberration Scale (PABS), Social Anhedonia Scale (SAS), and Physical Anhedonia Scale (PAS) were administered to 98 relatives of schizophrenic patients along with a measure of personality disorders (the Personality Diagnostic Questionnaire-Revised). Hierarchical regression analysis indicated that the schizotypal and borderline personality disorder (PD) scales explained significant variance in both the MIS and PABS; the avoidant PD scale also explained significant variance in the PABS. The schizoid, paranoid, and avoidant PD scales explained significant variance in the SAS. Sibling intraclass correlations indicated a significant heritability of 0.62 for the PABS.

Original language	English
Pages (from-to)	390-394
Number of pages	5
Journal	Journal of Abnormal Psychology
Volume	104
Issue number	2
DOIs	https://doi.org/10.1037/0021-843X.104.2.390
State	Published - May 1995

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title = "Correlates of Psychosis Proneness in Relatives of Schizophrenic Patients",

abstract = "The Magical Ideation Scale (MIS), Perceptual Aberration Scale (PABS), Social Anhedonia Scale (SAS), and Physical Anhedonia Scale (PAS) were administered to 98 relatives of schizophrenic patients along with a measure of personality disorders (the Personality Diagnostic Questionnaire-Revised). Hierarchical regression analysis indicated that the schizotypal and borderline personality disorder (PD) scales explained significant variance in both the MIS and PABS; the avoidant PD scale also explained significant variance in the PABS. The schizoid, paranoid, and avoidant PD scales explained significant variance in the SAS. Sibling intraclass correlations indicated a significant heritability of 0.62 for the PABS.",

author = "Lyons, \{Michael J.\} and Rosemary Toomey and Faraone, \{Stephen V.\} and Kremen, \{William S.\} and Yeung, \{Albert S.\} and Tsuang, \{Ming T.\}",

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AU - Lyons, Michael J.

AU - Toomey, Rosemary

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AU - Kremen, William S.

AU - Yeung, Albert S.

AU - Tsuang, Ming T.

PY - 1995/5

Y1 - 1995/5

N2 - The Magical Ideation Scale (MIS), Perceptual Aberration Scale (PABS), Social Anhedonia Scale (SAS), and Physical Anhedonia Scale (PAS) were administered to 98 relatives of schizophrenic patients along with a measure of personality disorders (the Personality Diagnostic Questionnaire-Revised). Hierarchical regression analysis indicated that the schizotypal and borderline personality disorder (PD) scales explained significant variance in both the MIS and PABS; the avoidant PD scale also explained significant variance in the PABS. The schizoid, paranoid, and avoidant PD scales explained significant variance in the SAS. Sibling intraclass correlations indicated a significant heritability of 0.62 for the PABS.

AB - The Magical Ideation Scale (MIS), Perceptual Aberration Scale (PABS), Social Anhedonia Scale (SAS), and Physical Anhedonia Scale (PAS) were administered to 98 relatives of schizophrenic patients along with a measure of personality disorders (the Personality Diagnostic Questionnaire-Revised). Hierarchical regression analysis indicated that the schizotypal and borderline personality disorder (PD) scales explained significant variance in both the MIS and PABS; the avoidant PD scale also explained significant variance in the PABS. The schizoid, paranoid, and avoidant PD scales explained significant variance in the SAS. Sibling intraclass correlations indicated a significant heritability of 0.62 for the PABS.

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DO - 10.1037/0021-843X.104.2.390

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SP - 390

EP - 394

JO - Journal of Abnormal Psychology

JF - Journal of Abnormal Psychology

IS - 2

ER -

Correlates of Psychosis Proneness in Relatives of Schizophrenic Patients

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