Cross-modal innervation of primary visual cortex by auditory fibers in congenitally anophthalmic mice

L. K. Laemle; N. L. Strominger; D. O. Carpenter

doi:10.1016/j.neulet.2005.11.020

Cross-modal innervation of primary visual cortex by auditory fibers in congenitally anophthalmic mice

L. K. Laemle
, N. L. Strominger
, D. O. Carpenter

Environmental Health Sciences

University at Albany

Rutgers - The State University of New Jersey, New Brunswick
SUNY Albany
Albany Medical College

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Auditory-visual cross-modal innervation was examined in control (sighted, ZRDCT-N) and congenitally anophthalmic (eyeless, ZRDCT-AN) mice using electrophysiological recording and pathway tracing with carbocyanine dyes. Electrophysiological data demonstrate that the primary visual cortex of congenitally eyeless, blind, mice receives auditory stimuli. Neuroanatomical data demonstrate a direct connection between the inferior colliculus (IC) and visual cortex. Our experiments provide new information about how the brain adapts to the loss of sight.

Original language	English
Pages (from-to)	108-112
Number of pages	5
Journal	Neuroscience Letters
Volume	396
Issue number	2
DOIs	https://doi.org/10.1016/j.neulet.2005.11.020
State	Published - Mar 27 2006

Keywords

Anophthalmic mice
Auditory pathway
Cross-modal innervation
Visual cortex

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10.1016/j.neulet.2005.11.020

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abstract = "Auditory-visual cross-modal innervation was examined in control (sighted, ZRDCT-N) and congenitally anophthalmic (eyeless, ZRDCT-AN) mice using electrophysiological recording and pathway tracing with carbocyanine dyes. Electrophysiological data demonstrate that the primary visual cortex of congenitally eyeless, blind, mice receives auditory stimuli. Neuroanatomical data demonstrate a direct connection between the inferior colliculus (IC) and visual cortex. Our experiments provide new information about how the brain adapts to the loss of sight.",

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T1 - Cross-modal innervation of primary visual cortex by auditory fibers in congenitally anophthalmic mice

AU - Laemle, L. K.

AU - Strominger, N. L.

AU - Carpenter, D. O.

PY - 2006/3/27

Y1 - 2006/3/27

N2 - Auditory-visual cross-modal innervation was examined in control (sighted, ZRDCT-N) and congenitally anophthalmic (eyeless, ZRDCT-AN) mice using electrophysiological recording and pathway tracing with carbocyanine dyes. Electrophysiological data demonstrate that the primary visual cortex of congenitally eyeless, blind, mice receives auditory stimuli. Neuroanatomical data demonstrate a direct connection between the inferior colliculus (IC) and visual cortex. Our experiments provide new information about how the brain adapts to the loss of sight.

AB - Auditory-visual cross-modal innervation was examined in control (sighted, ZRDCT-N) and congenitally anophthalmic (eyeless, ZRDCT-AN) mice using electrophysiological recording and pathway tracing with carbocyanine dyes. Electrophysiological data demonstrate that the primary visual cortex of congenitally eyeless, blind, mice receives auditory stimuli. Neuroanatomical data demonstrate a direct connection between the inferior colliculus (IC) and visual cortex. Our experiments provide new information about how the brain adapts to the loss of sight.

KW - Anophthalmic mice

KW - Auditory pathway

KW - Cross-modal innervation

KW - Visual cortex

UR - https://www.scopus.com/pages/publications/33244493353

U2 - 10.1016/j.neulet.2005.11.020

DO - 10.1016/j.neulet.2005.11.020

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SP - 108

EP - 112

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 2

ER -

Cross-modal innervation of primary visual cortex by auditory fibers in congenitally anophthalmic mice

Abstract

Keywords

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