Abstract
This paper summarizes the engineering development of our lab for endoscopic optical coherence tomography toward the ultimate goal to image bladder micro architecture and to diagnose bladder cancers. To test the utility and potential limitations of OCT setups for bladder tumor diagnosis, we used a rat bladder cancer model to track the morphological changes following tumor growth. Image results are presented, suggesting that OCT is able to differentiate cancerous lesions from inflammatory lesions based on OCT characterizations of epithelial thickness and backscattering changes of bladder tissue.
| Original language | English |
|---|---|
| Pages (from-to) | 56-61 |
| Number of pages | 6 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 5316 |
| DOIs | |
| State | Published - 2004 |
| Event | Progress in Biomedical Optics and Imaging - Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII - San Jose, CA, United States Duration: Jan 26 2004 → Jan 28 2004 |
Keywords
- Backscattering
- Bladder tumor
- Hyperplasia
- Imaging
- Laser scanning cystoscopy
- Microscopy
- Ncoplasia
- Optical coherence tomography
- Optical modeling
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