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Development of a Medication-Use Evaluation Template for Andexanet Alfa in the Reversal of Anticoagulation With Factor Xa Inhibitors

  • Toni Fera
  • , Allison Burnett
  • , Jessica Grandoni
  • , Mary R. Moore
  • , Barbara B. Nussbaum
  • , Charles V. Pollack
  • , Anne E. Rose
  • , Sarah A. Spinler
  • , Michael B. Streiff
  • , Charles J. Turck
  • , John Fanikos
  • Project Consultant
  • University of New Mexico
  • Brigham and Women’s Hospital
  • Partners HealthCare
  • American Society of Health-System Pharmacists
  • University of Mississippi
  • University of Wisconsin-Madison
  • Johns Hopkins University
  • Scientia Perpetuam
  • North American Thrombosis Forum

Research output: Contribution to journalComment/debate

Abstract

Medication-use evaluations are meant to ensure that medication-use processes are consistent with prevailing standards of care, assure optimal use of therapy, and reduce the risk of medication-related problems. Reversal agents for direct oral anticoagulants are a worthy focus for medication-use evaluations for reasons of efficacy, safety, and cost. A multidisciplinary team of experts developed 2 medication-use evaluation templates illustrating the application of professional society guidelines to the appropriate use of andexanet alfa.

Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalJournal of Pharmacy Practice
Volume38
Issue number1
DOIs
StatePublished - Feb 2025

Keywords

  • andexanet alfa
  • anticoagulant reversal agents
  • hemorrhage
  • intracranial hemorrhages
  • medication review

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