Abstract
There is an unmet medical need for tolerable and effective androgenetic alopecia therapies. Emerging treatments include CRISPR-Cas9 (clustered, regularly interspaced, short palindromic repeats-CRISPR associated protein 9) gene editing, small interfering RNA (siRNA), microRNA (miRNA), and tissue engineering. However, extensive research investigating the safety and efficacy of these modalities is required before they can be employed in human studies.
| Original language | English |
|---|---|
| Title of host publication | Procedures in Cosmetic Dermatology |
| Subtitle of host publication | Hair Restoration |
| Publisher | Elsevier |
| Pages | 207-218 |
| Number of pages | 12 |
| ISBN (Electronic) | 9780323829212 |
| ISBN (Print) | 9780323829229 |
| DOIs | |
| State | Published - Jan 1 2023 |
Keywords
- Androgenetic alopecia
- CRISPR
- CRISPR-Cas9
- RNA
- devices
- emerging
- gene therapy
- genomic therapies
- miRNA
- siRNA
- therapies
- tissue engineering
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