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Disease progression in pediatric multiple sclerosis: Disparities between physical and neurocognitive outcomes

  • Women and Children's Hospital of Buffalo
  • SUNY Buffalo

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Growing information regarding the neurocognitive burden of pediatric multiple sclerosis (MS) has become available in recent years. Whereas natural history studies suggest a longer time to irreversible disability in the pediatric population with MS than in the adult MS population, increasing knowledge suggests a relatively rapid accrual of cognitive deficits in this young population. This article will explore this paradox, taking into account studies that have focused on neuroimaging, cognition and outcomes in pediatric MS.

Original languageEnglish
Pages (from-to)433-440
Number of pages8
JournalExpert Review of Neurotherapeutics
Volume11
Issue number3
DOIs
StatePublished - Mar 2011

Keywords

  • MRI
  • adolescent
  • cognition
  • demyelinating disease
  • disease progression
  • multiple sclerosis
  • neurocognitive testing
  • pediatric
  • quality of life

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