Do patients with severe aortic stenosis and progressive left ventricular ejection fraction decline 50 to 59% remain asymptomatic?

Muhammad Etiwy; Adam N. Berman; Michael H. Picard; Chiara Fraccaro; Nicole Karam; Meagan M. Wasfy; Cynthia Taub; John Hsu; James L. Januzzi; Jason H. Wasfy

doi:10.1016/j.jtcvs.2025.09.019

Do patients with severe aortic stenosis and progressive left ventricular ejection fraction decline 50 to 59% remain asymptomatic?

Muhammad Etiwy
, Adam N. Berman
, Michael H. Picard
, Chiara Fraccaro
, Nicole Karam
, Meagan M. Wasfy
, Cynthia Taub
, John Hsu
, James L. Januzzi
, Jason H. Wasfy

Medicine

Upstate Medical University

Dartmouth College
Harvard University
New York University
University of Padua
AP-HP
and Harvard Clinical Research Institute

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	e50-e54
Journal	Journal of Thoracic and Cardiovascular Surgery
Volume	171
Issue number	3
DOIs	https://doi.org/10.1016/j.jtcvs.2025.09.019
State	Published - Mar 2026

Access to Document

10.1016/j.jtcvs.2025.09.019

Cite this

Etiwy, M., Berman, A. N., Picard, M. H., Fraccaro, C., Karam, N., Wasfy, M. M., Taub, C., Hsu, J., Januzzi, J. L., & Wasfy, J. H. (2026). Do patients with severe aortic stenosis and progressive left ventricular ejection fraction decline 50 to 59% remain asymptomatic? Journal of Thoracic and Cardiovascular Surgery, 171(3), e50-e54. https://doi.org/10.1016/j.jtcvs.2025.09.019

@article{6bdea54c4d924b989031aadca4c147bf,

title = "Do patients with severe aortic stenosis and progressive left ventricular ejection fraction decline 50 to 59\% remain asymptomatic?",

author = "Muhammad Etiwy and Berman, \{Adam N.\} and Picard, \{Michael H.\} and Chiara Fraccaro and Nicole Karam and Wasfy, \{Meagan M.\} and Cynthia Taub and John Hsu and Januzzi, \{James L.\} and Wasfy, \{Jason H.\}",

year = "2026",

month = mar,

doi = "10.1016/j.jtcvs.2025.09.019",

language = "English",

volume = "171",

pages = "e50--e54",

journal = "Journal of Thoracic and Cardiovascular Surgery",

issn = "0022-5223",