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Dosimetric Characterization of Photobiomodulation Devices at 660nm and 810nm for Clinical Applications in Dentistry

  • Dennis Sourvanos
  • , Timothy C. Zhu
  • , Andreea Dimofte
  • , Theresa M. Busch
  • , Weibing Yang
  • , Praveen Arany
  • , James D. Carroll
  • , Todd Schoenbaum
  • , Joseph P. Fiorellini
  • University of Pennsylvania
  • THOR Photomedicine
  • Augusta University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Photobiomodulation (PBM) uses red and near-infrared light (600-1, 100nm) as a noninvasive treatment in dentistry. Effective PBM therapy relies on understanding dosimetry variables like energy, focal spot size, irradiation, fluence rate, light distribution, and tissue interaction. This study evaluates FDA-approved PBM devices at 660nm and 810nm wavelengths, focusing on these parameters in clinical settings to enhance the effectiveness of PBM therapy and guide future protocols. Light distribution measurements were taken in a heterogeneous medium using an isotropic detector at distances from 0 to 30 mm. Both linear and nonlinear wavelength fitting algorithms assessed optical parameters, such as light absorption (µa), scattering (µ's), and effective attenuation (µ-eff). The fluence rate was calculated in mW/cm2, and data analysis will determine the mean and standard deviation for each wavelength. Results indicate marked differences in light distribution between 660nm and 810nm devices. Variations in fluence rates may affect tissue interaction and therapeutic outcomes. This study highlights the need for tailored device settings based on clinical context and target tissue to improve dental PBM protocols. Future research should link these dosimetry results with clinical outcomes for enhanced treatment precision.

Original languageEnglish
Title of host publicationMechanisms of Photobiomodulation Therapy XIX
EditorsAnn Liebert, Jeri-Anne Lyons, James D. Carroll
PublisherSPIE
ISBN (Electronic)9781510683426
DOIs
StatePublished - 2025
EventMechanisms of Photobiomodulation Therapy XIX 2025 - San Francisco, United States
Duration: Jan 25 2025Jan 26 2025

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13297

Conference

ConferenceMechanisms of Photobiomodulation Therapy XIX 2025
Country/TerritoryUnited States
CitySan Francisco
Period01/25/2501/26/25

Keywords

  • Dentistry
  • Dosimetry
  • Oral Medicine
  • PBM
  • Periodontics
  • Photobiomodulation
  • Physics

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