Abstract
The ultrastructural appearance of a highly motile population of spermatozoa from a fertile donor was evaluated following antibody labeling with each of several sperm head-directed anti-sperm antibodies (ASAs) and subsequent incubation in a capacitating medium in vitro. Acrosomes were classified into categories which are believed to represent stages in the acrosome reaction. Quantitative analysis revealed no difference in acrosomal morphology of antibody-labeled sperm between treatment groups despite a varying degree of enhancement or inhibition of sperm egg-penetrating ability. We conclude that ASAs affect gamete interaction through mechanisms other than an alteration in the acrosome reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 653-657 |
| Number of pages | 5 |
| Journal | Human Reproduction |
| Volume | 4 |
| Issue number | 6 |
| DOIs | |
| State | Published - Aug 1989 |
Keywords
- Acrosomal reaction
- Anti-sperm antibodies
- Oolemma
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