Effects of morphine on tumour growth

Mads Rasmussen; Wei Zhu; Jan Tønnesen; Patrick Cadet; Else Tønnesen; George B. Stefano

Effects of morphine on tumour growth

Mads Rasmussen
, Wei Zhu
, Jan Tønnesen
, Patrick Cadet
, Else Tønnesen
, George B. Stefano

Biological Sciences

Old Westbury

Aarhus University

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Endogenous opiate alkaloids, such as morphine, and their peptide counterparts have been implicated in a wide variety of pharmacological and physiological functions. In addition to their use in the treatment of pain, opioids, appears to be important in the growth regulation of normal and neoplastic tissue. This review will focus on the influence of endogenous and exogenous opioids on tumour growth, with emphasis on immunoregulatory and anti-proliferative mechanisms.

Original language	English
Pages (from-to)	193-198
Number of pages	6
Journal	Neuroendocrinology Letters
Volume	23
Issue number	3
State	Published - 2002

Keywords

Apoptosis
Cancer
Endogenous opioids
Morphine
Neoplasia
Nitric oxide

Cite this

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title = "Effects of morphine on tumour growth",

abstract = "Endogenous opiate alkaloids, such as morphine, and their peptide counterparts have been implicated in a wide variety of pharmacological and physiological functions. In addition to their use in the treatment of pain, opioids, appears to be important in the growth regulation of normal and neoplastic tissue. This review will focus on the influence of endogenous and exogenous opioids on tumour growth, with emphasis on immunoregulatory and anti-proliferative mechanisms.",

keywords = "Apoptosis, Cancer, Endogenous opioids, Morphine, Neoplasia, Nitric oxide",

author = "Mads Rasmussen and Wei Zhu and Jan T{\o}nnesen and Patrick Cadet and Else T{\o}nnesen and Stefano, \{George B.\}",

year = "2002",

language = "English",

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pages = "193--198",

journal = "Neuroendocrinology Letters",

issn = "0172-780X",

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TY - JOUR

T1 - Effects of morphine on tumour growth

AU - Rasmussen, Mads

AU - Zhu, Wei

AU - Tønnesen, Jan

AU - Cadet, Patrick

AU - Tønnesen, Else

AU - Stefano, George B.

PY - 2002

Y1 - 2002

N2 - Endogenous opiate alkaloids, such as morphine, and their peptide counterparts have been implicated in a wide variety of pharmacological and physiological functions. In addition to their use in the treatment of pain, opioids, appears to be important in the growth regulation of normal and neoplastic tissue. This review will focus on the influence of endogenous and exogenous opioids on tumour growth, with emphasis on immunoregulatory and anti-proliferative mechanisms.

AB - Endogenous opiate alkaloids, such as morphine, and their peptide counterparts have been implicated in a wide variety of pharmacological and physiological functions. In addition to their use in the treatment of pain, opioids, appears to be important in the growth regulation of normal and neoplastic tissue. This review will focus on the influence of endogenous and exogenous opioids on tumour growth, with emphasis on immunoregulatory and anti-proliferative mechanisms.

KW - Apoptosis

KW - Cancer

KW - Endogenous opioids

KW - Morphine

KW - Neoplasia

KW - Nitric oxide

UR - https://www.scopus.com/pages/publications/0035989479

M3 - Review article

C2 - 12080278

SN - 0172-780X

VL - 23

SP - 193

EP - 198

JO - Neuroendocrinology Letters

JF - Neuroendocrinology Letters

IS - 3

ER -

Effects of morphine on tumour growth

Abstract

Keywords

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