Ependymal tumors

Christine E. Fuller; Sonia Narendra; Ioana Tolicica

doi:10.1007/978-1-4419-1062-2_5

Ependymal tumors

Christine E. Fuller
, Sonia Narendra
, Ioana Tolicica

Pathology

Upstate Medical University

SUNY Upstate Medical University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

Abstract

A group of glial tumors exhibiting ependymal differentiation including subependymoma (WHO grade I), myxopapillary ependymoma (WHO grade I), ependymoma (WHO grade II; variants including cellular, tanycytic, papillary, and clear cell), and anaplastic ependymoma (WHO grade III). Most are sporadic; ependymomas may be seen as part of neurofibromatosis type 2, a hereditary cancer predisposition syndrome with germline mutation of NF2/Merlin gene. Recent evidence supports radial glia as the candidate cell of origin for ependymomas; subependymomas appear to derive from subependymal glial precursors.

Original language	English
Title of host publication	Atlas of Pediatric Brain Tumors
Publisher	Springer New York
Pages	47-59
Number of pages	13
ISBN (Print)	9781441910615
DOIs	https://doi.org/10.1007/978-1-4419-1062-2_5
State	Published - 2010

Keywords

Anaplastic ependymoma
Clear cell ependymoma
Ependymoma
Myxopapillary ependymoma
Papillary ependymoma
Subependymoma

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10.1007/978-1-4419-1062-2_5

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title = "Ependymal tumors",

abstract = "A group of glial tumors exhibiting ependymal differentiation including subependymoma (WHO grade I), myxopapillary ependymoma (WHO grade I), ependymoma (WHO grade II; variants including cellular, tanycytic, papillary, and clear cell), and anaplastic ependymoma (WHO grade III). Most are sporadic; ependymomas may be seen as part of neurofibromatosis type 2, a hereditary cancer predisposition syndrome with germline mutation of NF2/Merlin gene. Recent evidence supports radial glia as the candidate cell of origin for ependymomas; subependymomas appear to derive from subependymal glial precursors.",

keywords = "Anaplastic ependymoma, Clear cell ependymoma, Ependymoma, Myxopapillary ependymoma, Papillary ependymoma, Subependymoma",

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year = "2010",

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T1 - Ependymal tumors

AU - Fuller, Christine E.

AU - Narendra, Sonia

AU - Tolicica, Ioana

PY - 2010

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N2 - A group of glial tumors exhibiting ependymal differentiation including subependymoma (WHO grade I), myxopapillary ependymoma (WHO grade I), ependymoma (WHO grade II; variants including cellular, tanycytic, papillary, and clear cell), and anaplastic ependymoma (WHO grade III). Most are sporadic; ependymomas may be seen as part of neurofibromatosis type 2, a hereditary cancer predisposition syndrome with germline mutation of NF2/Merlin gene. Recent evidence supports radial glia as the candidate cell of origin for ependymomas; subependymomas appear to derive from subependymal glial precursors.

AB - A group of glial tumors exhibiting ependymal differentiation including subependymoma (WHO grade I), myxopapillary ependymoma (WHO grade I), ependymoma (WHO grade II; variants including cellular, tanycytic, papillary, and clear cell), and anaplastic ependymoma (WHO grade III). Most are sporadic; ependymomas may be seen as part of neurofibromatosis type 2, a hereditary cancer predisposition syndrome with germline mutation of NF2/Merlin gene. Recent evidence supports radial glia as the candidate cell of origin for ependymomas; subependymomas appear to derive from subependymal glial precursors.

KW - Anaplastic ependymoma

KW - Clear cell ependymoma

KW - Ependymoma

KW - Myxopapillary ependymoma

KW - Papillary ependymoma

KW - Subependymoma

UR - https://www.scopus.com/pages/publications/84857507332

U2 - 10.1007/978-1-4419-1062-2_5

DO - 10.1007/978-1-4419-1062-2_5

M3 - Chapter

SN - 9781441910615

SP - 47

EP - 59

BT - Atlas of Pediatric Brain Tumors

PB - Springer New York

ER -

Ependymal tumors

Abstract

Keywords

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