Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)

J. T. Nuckols; Y. J.S. Huang; S. Higgs; A. L. Miller; R. B. Pyles; H. M. Spratt; K. M. Horne; D. L. Vanlandingham

doi:10.1093/jme/tjv017

Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)

J. T. Nuckols
, Y. J.S. Huang
, S. Higgs
, A. L. Miller
, R. B. Pyles
, H. M. Spratt
, K. M. Horne
, D. L. Vanlandingham

Neurosurgery

Upstate Medical University

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 × 10⁵ PFU/ml of CHIKV and 3.2 × 10⁶ FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.

Original language	English
Pages (from-to)	447-451
Number of pages	5
Journal	Journal of Medical Entomology
Volume	52
Issue number	3
DOIs	https://doi.org/10.1093/jme/tjv017
State	Published - May 1 2015

Keywords

Aedes aegypti
Aedes albopictus
Chikungunya
Dengue
Transmission

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10.1093/jme/tjv017

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title = "Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)",

abstract = "The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 × 105 PFU/ml of CHIKV and 3.2 × 106 FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.",

keywords = "Aedes aegypti, Aedes albopictus, Chikungunya, Dengue, Transmission",

author = "Nuckols, \{J. T.\} and Huang, \{Y. J.S.\} and S. Higgs and Miller, \{A. L.\} and Pyles, \{R. B.\} and Spratt, \{H. M.\} and Horne, \{K. M.\} and Vanlandingham, \{D. L.\}",

year = "2015",

month = may,

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doi = "10.1093/jme/tjv017",

language = "English",

volume = "52",

pages = "447--451",

journal = "Journal of Medical Entomology",

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T1 - Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)

AU - Nuckols, J. T.

AU - Huang, Y. J.S.

AU - Higgs, S.

AU - Miller, A. L.

AU - Pyles, R. B.

AU - Spratt, H. M.

AU - Horne, K. M.

AU - Vanlandingham, D. L.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 × 105 PFU/ml of CHIKV and 3.2 × 106 FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.

AB - The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 × 105 PFU/ml of CHIKV and 3.2 × 106 FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.

KW - Aedes aegypti

KW - Aedes albopictus

KW - Chikungunya

KW - Dengue

KW - Transmission

UR - https://www.scopus.com/pages/publications/84936938670

U2 - 10.1093/jme/tjv017

DO - 10.1093/jme/tjv017

M3 - Article

C2 - 26334820

SN - 0022-2585

VL - 52

SP - 447

EP - 451

JO - Journal of Medical Entomology

JF - Journal of Medical Entomology

IS - 3

ER -

Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)

Abstract

Keywords

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