Evasion of natural killer cells by influenza virus

Hailong Guo; Pawan Kumar; Subramaniam Malarkannan

doi:10.1189/jlb.0610319

Evasion of natural killer cells by influenza virus

Hailong Guo
, Pawan Kumar
, Subramaniam Malarkannan

Microbiology and Immunology

Stony Brook University

University of Rochester
BloodCenter of Wisconsin
Medical College of Wisconsin

Research output: Contribution to journal › Short survey › peer-review

32 Scopus citations

Abstract

NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.

Original language	English
Pages (from-to)	189-194
Number of pages	6
Journal	Journal of Leukocyte Biology
Volume	89
Issue number	2
DOIs	https://doi.org/10.1189/jlb.0610319
State	Published - Feb 2011

Keywords

Cellular immunology
Immune evasion
Infectious

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10.1189/jlb.0610319

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title = "Evasion of natural killer cells by influenza virus",

abstract = "NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.",

keywords = "Cellular immunology, Immune evasion, Infectious",

author = "Hailong Guo and Pawan Kumar and Subramaniam Malarkannan",

year = "2011",

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doi = "10.1189/jlb.0610319",

language = "English",

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TY - JOUR

T1 - Evasion of natural killer cells by influenza virus

AU - Guo, Hailong

AU - Kumar, Pawan

AU - Malarkannan, Subramaniam

PY - 2011/2

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N2 - NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.

AB - NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.

KW - Cellular immunology

KW - Immune evasion

KW - Infectious

UR - https://www.scopus.com/pages/publications/79951894460

U2 - 10.1189/jlb.0610319

DO - 10.1189/jlb.0610319

M3 - Short survey

C2 - 20682623

SN - 0741-5400

VL - 89

SP - 189

EP - 194

JO - Journal of Leukocyte Biology

JF - Journal of Leukocyte Biology

IS - 2

ER -

Evasion of natural killer cells by influenza virus

Abstract

Keywords

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