Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

Toshihiro Mita; Akira Kaneko; Jeffery K. Lum; Innocent L. Zungu; Takahiro Tsukahara; Hideaki Eto; Takatoshi Kobayakawa; Anders Björkman; Kazuyuki Tanabe

doi:10.1016/j.molbiopara.2004.01.011

Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

Toshihiro Mita
, Akira Kaneko
, Jeffery K. Lum
, Innocent L. Zungu
, Takahiro Tsukahara
, Hideaki Eto
, Takatoshi Kobayakawa
, Anders Björkman
, Kazuyuki Tanabe

Anthropology

Binghamton University

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Original language	English
Pages (from-to)	159-163
Number of pages	5
Journal	Molecular and Biochemical Parasitology
Volume	135
Issue number	1
DOIs	https://doi.org/10.1016/j.molbiopara.2004.01.011
State	Published - May 2004

Keywords

Back mutation
Chloroquine
P. falciparum chloroquine resistance transporter gene
P. falciparum multiple drug resistance gene 1
PCR
Plasmodium falciparum
Polymerase chain reaction
pfcrt
pfmdr1

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10.1016/j.molbiopara.2004.01.011

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Mita, T., Kaneko, A., Lum, J. K., Zungu, I. L., Tsukahara, T., Eto, H., Kobayakawa, T., Björkman, A., & Tanabe, K. (2004). Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi. Molecular and Biochemical Parasitology, 135(1), 159-163. https://doi.org/10.1016/j.molbiopara.2004.01.011

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title = "Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi",

keywords = "Back mutation, Chloroquine, P. falciparum chloroquine resistance transporter gene, P. falciparum multiple drug resistance gene 1, PCR, Plasmodium falciparum, Polymerase chain reaction, pfcrt, pfmdr1",

author = "Toshihiro Mita and Akira Kaneko and Lum, \{Jeffery K.\} and Zungu, \{Innocent L.\} and Takahiro Tsukahara and Hideaki Eto and Takatoshi Kobayakawa and Anders Bj{\"o}rkman and Kazuyuki Tanabe",

year = "2004",

month = may,

doi = "10.1016/j.molbiopara.2004.01.011",

language = "English",

volume = "135",

pages = "159--163",

journal = "Molecular and Biochemical Parasitology",

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Mita, T, Kaneko, A, Lum, JK, Zungu, IL, Tsukahara, T, Eto, H, Kobayakawa, T, Björkman, A & Tanabe, K 2004, 'Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi', Molecular and Biochemical Parasitology, vol. 135, no. 1, pp. 159-163. https://doi.org/10.1016/j.molbiopara.2004.01.011

TY - JOUR

T1 - Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

AU - Mita, Toshihiro

AU - Kaneko, Akira

AU - Lum, Jeffery K.

AU - Zungu, Innocent L.

AU - Tsukahara, Takahiro

AU - Eto, Hideaki

AU - Kobayakawa, Takatoshi

AU - Björkman, Anders

AU - Tanabe, Kazuyuki

PY - 2004/5

Y1 - 2004/5

KW - Back mutation

KW - Chloroquine

KW - P. falciparum chloroquine resistance transporter gene

KW - P. falciparum multiple drug resistance gene 1

KW - PCR

KW - Plasmodium falciparum

KW - Polymerase chain reaction

KW - pfcrt

KW - pfmdr1

UR - https://www.scopus.com/pages/publications/1842662623

U2 - 10.1016/j.molbiopara.2004.01.011

DO - 10.1016/j.molbiopara.2004.01.011

M3 - Article

C2 - 15287598

SN - 0166-6851

VL - 135

SP - 159

EP - 163

JO - Molecular and Biochemical Parasitology

JF - Molecular and Biochemical Parasitology

IS - 1

ER -

Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi

Keywords

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