GOTreePlus: An interactive gene ontology browser

Bongshin Lee; Kristy Brown; Yetrib Hathout; Jinwook Seo

doi:10.1093/bioinformatics/btn068

GOTreePlus: An interactive gene ontology browser

Bongshin Lee
, Kristy Brown
, Yetrib Hathout
, Jinwook Seo

Pharmaceutical Sciences

Binghamton University

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Summary: We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified.

Original language	English
Pages (from-to)	1026-1028
Number of pages	3
Journal	Bioinformatics
Volume	24
Issue number	7
DOIs	https://doi.org/10.1093/bioinformatics/btn068
State	Published - Apr 2008

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title = "GOTreePlus: An interactive gene ontology browser",

abstract = "Summary: We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified.",

author = "Bongshin Lee and Kristy Brown and Yetrib Hathout and Jinwook Seo",

year = "2008",

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AU - Brown, Kristy

AU - Hathout, Yetrib

AU - Seo, Jinwook

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N2 - Summary: We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified.

AB - Summary: We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified.

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DO - 10.1093/bioinformatics/btn068

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JO - Bioinformatics

JF - Bioinformatics

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GOTreePlus: An interactive gene ontology browser

Abstract

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