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Latest advances in aging research and drug discovery

  • Daniela Bakula
  • , Andrea Ablasser
  • , Adriano Aguzzi
  • , Adam Antebi
  • , Nir Barzilai
  • , Martin Immanuel Bittner
  • , Martin Borch Jensen
  • , Cornelis F. Calkhoven
  • , Danica Chen
  • , Aubrey D.N.J. de Grey
  • , Jerome N. Feige
  • , Anastasia Georgievskaya
  • , Vadim N. Gladyshev
  • , Tyler Golato
  • , Andrei V. Gudkov
  • , Thorsten Hoppe
  • , Matt Kaeberlein
  • , Pekka Katajisto
  • , Brian K. Kennedy
  • , Unmesh Lal
  • Ana Martin-Villalba, Alexey A. Moskalev, Ivan Ozerov, Michael A. Petr, Reason, David C. Rubinsztein, Alexander Tyshkovskiy, Quentin Vanhaelen, Alex Zhavoronkov, Morten Scheibye-Knudsen
  • University of Copenhagen
  • Swiss Federal Institute of Technology Lausanne
  • University of Zurich
  • Max Planck Institute for Biology of Ageing
  • University of Cologne
  • Albert Einstein College of Medicine
  • Arctoris Ltd
  • Gordian Biotechnology
  • University of Groningen
  • University of California at Berkeley
  • SENS Research Foundation
  • Nestle
  • Haut. AI
  • Brigham and Women’s Hospital
  • Molecule
  • University of Washington
  • Karolinska Institutet
  • University of Helsinki
  • National University of Singapore
  • National University Healthy System
  • Buck Institute for Age Research
  • Frost and Sullivan
  • German Cancer Research Center
  • Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
  • Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences
  • Moscow Institute of Physics and Technology
  • Insilico Medicine
  • Repair Biotechnologies, Inc.
  • University of Cambridge
  • Cambridge Biomedical Campus
  • Lomonosov Moscow State University

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to treat age-associated diseases. The field of aging research is rapidly expanding with multiple advances transpiring in many previously disconnected areas. Several major pharmaceutical, biotechnology, and consumer companies made aging research a priority and are building internal expertise, integrating aging research into traditional business models and exploring new go-to-market strategies. Many of these efforts are spearheaded by the latest advances in artificial intelligence, namely deep learning, including generative and reinforcement learning. To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled "Aging Research and Drug Discovery (ARDD)" held in the capital of the pharmaceutical industry, Basel, Switzerland (www.agingpharma.org). This ARDD collection contains summaries from the 6th annual meeting that explored aging mechanisms and new interventions in age-associated diseases. The 7th annual ARDD exhibition will transpire 2nd-4th of September, 2020, in Basel.

Original languageEnglish
Pages (from-to)9971-9981
Number of pages11
JournalAging
Volume11
Issue number22
DOIs
StatePublished - 2019

Keywords

  • Aging
  • Artificial intelligence
  • Drug discovery

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