Management of Acute Ischemic Thrombosis

Acute ischemic thrombosis in patients who have undergone neurosurgical procedures is a leading cause of mortality and long-term disability. Endovascular therapy has become an important treatment modality for acute ischemic thrombosis in these patients. Noninvasive imaging has dramatically changed the understanding of cerebral blood flow and the concepts of cerebrovascular reserve and salvageable penumbra. Increasingly, reliance on perfusion imaging to discern tissue viability and potential outcomes has become standard of care. With the advent of recent acute ischemic stroke trials, therapy for occlusive cerebrovascular disease is evolving, and understanding when to intervene is becoming paramount.