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Management of Infants Born with Disorders/Differences of Sex Development

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Precocious puberty has been a focus of interest for both the pediatric endocrinologist and the primary pediatrician for many years. The development and application of gonadotropin-releasing hormone (GnRH) agonist (GnRHa) therapy to treat central precocious puberty in the 1980s significantly changed our approach to this disorder. More recently, application of molecular biological techniques has led to a better understanding of the intricacies of regulation of gonadotropin and sex-steroid production characteristic of normal pubertal development and provided us with the tools to elucidate etiologies of previously uncharacterized disorders of precocious puberty.

Original languageEnglish
Title of host publicationPediatric Endocrinology
Subtitle of host publicationA Practical Clinical Guide, Fourth Edition
PublisherSpringer Nature
Pages721-746
Number of pages26
ISBN (Electronic)9783031662966
ISBN (Print)9783031662959
DOIs
StatePublished - Jan 1 2024

Keywords

  • Clitoral surgery
  • DSD and parental reaction
  • DSD and quality of life
  • Disorders of sex development/differences of sex development
  • Gender change
  • Gender dysphoria
  • Legal issues globally
  • Medical management of DSD
  • Non-categorical
  • Shared decision making

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