Measuring the basic physiological properties of synapses

Matthew A. Xu-Friedman

doi:10.1101/pdb.top089680

Measuring the basic physiological properties of synapses

Matthew A. Xu-Friedman

Biological Sciences

University at Buffalo

Research output: Contribution to journal › Article › peer-review

Abstract

Studying synaptic physiology remains an important endeavor for understanding the mechanisms that underlie neurotransmitter release as well as synaptic development and refinement. It is also critical to understanding brain function. The basic conceptual framework for synaptic physiology was worked out by Katz and colleagues and has coalesced around three factors: the number of releasable vesicles (N), the probability of release (P), and quantal size (Q). Here, I discuss a few key experiments related to these quantities and how they are assessed.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Cold Spring Harbor Protocols
Volume	2017
Issue number	1
DOIs	https://doi.org/10.1101/pdb.top089680
State	Published - Jan 2017

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Measuring the basic physiological properties of synapses

Abstract

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