Methods and Challenges in Quantitative Imaging Biomarker Development

Richard G. Abramson; Kirsteen R. Burton; John Paul J. Yu; Ernest M. Scalzetti; Thomas E. Yankeelov; Andrew B. Rosenkrantz; Mishal Mendiratta-Lala; Brian J. Bartholmai; Dhakshinamoorthy Ganeshan; Leon Lenchik; Rathan M. Subramaniam

doi:10.1016/j.acra.2014.09.001

Methods and Challenges in Quantitative Imaging Biomarker Development

Richard G. Abramson
, Kirsteen R. Burton
, John Paul J. Yu
, Ernest M. Scalzetti
, Thomas E. Yankeelov
, Andrew B. Rosenkrantz
, Mishal Mendiratta-Lala
, Brian J. Bartholmai
, Dhakshinamoorthy Ganeshan
, Leon Lenchik
, Rathan M. Subramaniam

Radiology

Upstate Medical University

Vanderbilt University
University of Toronto
University of California at San Francisco
New York University
Henry Ford Health System
Mayo Clinic Rochester, MN
University of Texas MD Anderson Cancer Center
Wake Forest University
Johns Hopkins University

Research output: Contribution to journal › Review article › peer-review

81 Scopus citations

Abstract

Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

Original language	English
Pages (from-to)	25-32
Number of pages	8
Journal	Academic Radiology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.acra.2014.09.001
State	Published - Jan 1 2015

Keywords

Biomarker development
Quantitative imaging
Radiology

Access to Document

10.1016/j.acra.2014.09.001

Cite this

@article{0d17997b8db44e66a2ee4e27b064cfd2,

title = "Methods and Challenges in Quantitative Imaging Biomarker Development",

abstract = "Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.",

keywords = "Biomarker development, Quantitative imaging, Radiology",

author = "Abramson, \{Richard G.\} and Burton, \{Kirsteen R.\} and Yu, \{John Paul J.\} and Scalzetti, \{Ernest M.\} and Yankeelov, \{Thomas E.\} and Rosenkrantz, \{Andrew B.\} and Mishal Mendiratta-Lala and Bartholmai, \{Brian J.\} and Dhakshinamoorthy Ganeshan and Leon Lenchik and Subramaniam, \{Rathan M.\}",

note = "Publisher Copyright: {\textcopyright} 2015 AUR.",

year = "2015",

month = jan,

day = "1",

doi = "10.1016/j.acra.2014.09.001",

language = "English",

volume = "22",

pages = "25--32",

journal = "Academic Radiology",

issn = "1076-6332",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Methods and Challenges in Quantitative Imaging Biomarker Development

AU - Abramson, Richard G.

AU - Burton, Kirsteen R.

AU - Yu, John Paul J.

AU - Scalzetti, Ernest M.

AU - Yankeelov, Thomas E.

AU - Rosenkrantz, Andrew B.

AU - Mendiratta-Lala, Mishal

AU - Bartholmai, Brian J.

AU - Ganeshan, Dhakshinamoorthy

AU - Lenchik, Leon

AU - Subramaniam, Rathan M.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

AB - Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

KW - Biomarker development

KW - Quantitative imaging

KW - Radiology

UR - https://www.scopus.com/pages/publications/84919416236

U2 - 10.1016/j.acra.2014.09.001

DO - 10.1016/j.acra.2014.09.001

M3 - Review article

C2 - 25481515

SN - 1076-6332

VL - 22

SP - 25

EP - 32

JO - Academic Radiology

JF - Academic Radiology

IS - 1

ER -

Methods and Challenges in Quantitative Imaging Biomarker Development

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this