MODELS | Acutely Dissociated Neurons

M. Stewart; R. K.S. Wong

doi:10.1016/B978-012373961-2.00356-8

MODELS | Acutely Dissociated Neurons

Physiology / Pharmacology

SUNY Downstate Health Sciences University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Abnormal cellular behavior can contribute to abnormal neuronal network activity, which is the hallmark of epilepsy. The acutely dissociated neuron is a valuable in vitro preparation for the study of cellular activity. Its advantages include superior access to many cellular properties, and exquisite control of the cellular environment. In addition, since this preparation focuses on single neurons, it is an appropriate and useful approach to studying neurons in those circumstances in which regional circuits are difficult to preserve (e.g., in neurosurgical surgical specimens).

Original language	English
Title of host publication	Encyclopedia of Basic Epilepsy Research
Publisher	Elsevier
Pages	735-740
Number of pages	6
ISBN (Electronic)	9780123739612
DOIs	https://doi.org/10.1016/B978-012373961-2.00356-8
State	Published - Jan 1 2009

Keywords

Action potential
Cortex
Current clamp
Ion channel
Ionic current
Pyramidal cell
Voltage clamp

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10.1016/B978-012373961-2.00356-8

Cite this

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KW - Cortex

KW - Current clamp

KW - Ion channel

KW - Ionic current

KW - Pyramidal cell

KW - Voltage clamp

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M3 - Chapter

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PB - Elsevier

ER -

MODELS | Acutely Dissociated Neurons

Abstract

Keywords

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