Abstract
The work summarized in this chapter is focused on the chemical constituents of Photofrin, its limitations and the strategy to take the advantage of porphyrins and reduced porphyrin-based compounds in developing improved imaging and imageguided dual function agents. Advantages of polyacrylamide (PAA)-based nanoparticles (NPs) for enhancing the tumor-avidity are also discussed. Such an approach under proper strategies could help in developing other targeted multifunctional, biodegradable, biocompatible and non-toxic NPs for cancer-imaging and therapy, which is otherwise difficult to achieve.
| Original language | English |
|---|---|
| Title of host publication | Handbook of Photodynamic Therapy |
| Subtitle of host publication | Updates on Recent Applications of Porphyrin-Based Compounds |
| Publisher | World Scientific Publishing Co. Pte Ltd |
| Pages | 3-44 |
| Number of pages | 42 |
| ISBN (Electronic) | 9789814719650 |
| ISBN (Print) | 9789814719643 |
| DOIs | |
| State | Published - Jun 1 2016 |
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